Comparison of generic and disease‐specific measures in their ability to detect differences in pressure ulcer clinical groups.

Patient‐reported outcomes can be included as end points in pressure ulcer (PU) intervention trials to provide information to inform decision‐making and improve the lives of patients. However, the challenge for researchers and clinicians is identifying and choosing an appropriate instrument for each...

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Publicado en:Wound Repair & Regeneration Vol. 27; no. 4; pp. 396 - 406
Autores principales: Rutherford, Claudia, Campbell, Rachel, Brown, Julia M., Smith, Isabelle, Costa, Daniel S. J., McGinnis, Elizabeth, Wilson, Lyn, Gilberts, Rachael, Brown, Sarah, Coleman, Susanne, Collier, Howard, Nixon, Jane E.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Jul2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2019
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/wrr.12716
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        atl: Comparison of generic and disease‐specific measures in their ability to detect differences in pressure ulcer clinical groups.
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          Rutherford, Claudia
          Campbell, Rachel
          Brown, Julia M.
          Smith, Isabelle
          Costa, Daniel S. J.
          McGinnis, Elizabeth
          Wilson, Lyn
          Gilberts, Rachael
          Brown, Sarah
          Coleman, Susanne
          Collier, Howard
          Nixon, Jane E.
        affil: Faculty of Science, School of Psychology, The University of Sydney, Sydney New South Wales, Australia
      sug:
        subj:
          Pressure Ulcer Diagnosis
          Pressure Ulcer Therapy
          Patient-Reported Outcomes
          Decision Making, Clinical
          Patient Attitudes
          Human
          Quality of Life
          Scales
          Questionnaires
          Validity
          Severity of Illness
          Functional Assessment
      ab: Patient‐reported outcomes can be included as end points in pressure ulcer (PU) intervention trials to provide information to inform decision‐making and improve the lives of patients. However, the challenge for researchers and clinicians is identifying and choosing an appropriate instrument for each particular application that suits their research questions and clinical context. To provide researchers and clinicians with the information needed to inform choice of patient‐reported outcome measures, we compared a generic and disease‐specific measures' ability to discriminate between clinical groups known to differ, and determined their responsiveness to change. We performed analyses on a subset of patients recruited to the PRESSURE 2 trial that completed the pressure ulcer quality of life instrument—prevention version (PU‐QOL‐P) and Short Form 12 Questionnaire (SF12) measures at baseline and 30‐day posttreatment. Known‐group validity and responsiveness‐to‐change analyses were conducted. The analysis sample consisted of 617 patients that completed both measures at baseline. Known‐group validity revealed that some PU‐QOL‐P symptoms and function scales differentiated between people with category 2 PUs and those without PUs. A less meaningful pattern of results was observed for the SF12 scales, suggesting that the PU‐QOL‐P is more sensitive to differences between PU and non‐PU populations. Responsiveness analysis revealed that the PU‐QOL‐P was more responsive in detecting disease severity than the SF12. The PU‐QOL‐P provides a standardized method for assessing PU‐specific symptoms and functioning outcomes and is suitable for quantifying the benefits of PU interventions from the patient's perspective. Generic measures are useful for group comparisons of global quality of life domains. Choice of measure for each particular application should be determined by the purpose of the measurement and the information required.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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