Attention and visuo-spatial function in children without cerebral palsy who were cooled for neonatal encephalopathy: a case-control study.

Objectives: Dorsal-stream functions are vulnerable to early brain injury associated with neonatal encephalopathy (NE) following perinatal asphyxia, even in children not developing cerebral palsy (CP). Since therapeutic hypothermia (TH) became the standard treatment for NE, the incidence of CP is red...

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Publicado en:Brain Injury Vol. 33; no. 7; pp. 894 - 899
Autores principales: Tonks, James, Cloke, Grace, Lee-Kelland, Richard, Jary, Sally, Thoresen, Marianne, Cowan, Frances M, Chakkarapani, Ela
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2019
Acceso en línea:Ver este registro en EBSCOhost
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    shortDbName: ccm
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    longDbName: CINAHL Complete
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        02699052
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      jtl: Brain Injury
      issn: 02699052
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      dt: 2019
      vid: 33
      iid: 7
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        137379726
        137379726
        137379726
        10.1080/02699052.2019.1597163
        137379726
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        atl: Attention and visuo-spatial function in children without cerebral palsy who were cooled for neonatal encephalopathy: a case-control study.
      aug:
        au:
          Tonks, James
          Cloke, Grace
          Lee-Kelland, Richard
          Jary, Sally
          Thoresen, Marianne
          Cowan, Frances M
          Chakkarapani, Ela
        affil: Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
      sug:
        subj:
          Infant, Newborn, Diseases Therapy
          Brain Diseases Therapy
          Hypothermia, Induced
          Cerebral Palsy
          Attention Evaluation
          Cognition Evaluation
          Visual Perception Evaluation
          Spatial Perception Evaluation
          Human
          Child
          Neuropsychological Tests
          Clinical Assessment Tools
          Treatment Outcomes
          Child: 6-12 years
      ab: Objectives: Dorsal-stream functions are vulnerable to early brain injury associated with neonatal encephalopathy (NE) following perinatal asphyxia, even in children not developing cerebral palsy (CP). Since therapeutic hypothermia (TH) became the standard treatment for NE, the incidence of CP is reduced but the impact on dorsal-stream functions is unknown. We aimed to compare dorsal-stream functions in TH-treated survivors of NE, without CP, with those of matched controls. Methods: We administered tests of dorsal-stream function to 29 case children aged 6-to-8 years treated with TH for NE and without CP, and 20 age, sex and social class matched controls. We used the Conner's Continuous Performance Test (CPT) 2nd Edition to assess attentiveness, based upon Hit Reaction Time (HRT) percentile score and HRT standard error percentile, the CPT HRT block change measure to assess sustained attention and the NEPSY-II block construction and arrows tests to assess visuo-spatial performance and mental rotation. Results: Case children performed significantly worse than controls on measures of attention and visuo-spatial function. Conclusions: Children given TH treatment for NE can have subtle attention difficulties with slower reaction times and reduced visuo-spatial processing. These findings illustrate the continued vulnerability of dorsal-stream functions following NE despite the use of TH.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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