Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia.

Background. Th17/Treg balance skews towards Th17 in ITP patient. IRF4 has been highlighted for its close relationship to the immunosuppressive function of Treg cells and the IL-17 synthesis in CD4+ T cells. This study was aimed at examining the effects of IRF4 to the Th17/Treg cells in patients with...

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Publicado en:	BioMed Research International pp. 1 - 12
Autores principales:	Tang, Meiwen, Cheng, Luya, Li, Feng, Wu, Boting, Chen, Pu, Zhan, Yanxia, Hua, Fanli, Min, Zhihui, Ke, Yang, Liu, Chanjuan, Yuan, Ling, Sun, Lihua, Chen, Hao, Ji, Lili, Cheng, Yunfeng
Formato:	pictorial research tables/charts Journal Article
Publicado:	Wiley-Blackwell 7/10/2019
Acceso en línea:	Ver este registro en EBSCOhost