Erosive pustular dermatosis of the scalp: A neutrophilic folliculitis within the spectrum of neutrophilic dermatoses: A clinicopathologic study of 30 cases.
Background: It is general opinion that histopathology is nonspecific and of little value in diagnosing erosive pustular dermatosis of the scalp (EPDS).Objectives: Clinicopathologic correlation of erosive pustular dermatosis of the scalp.Methods: We reviewed the clinical and pathologic records of pat...
| Published in: | Journal of the American Academy of Dermatology Vol. 81; no. 2; pp. 527 - 534 |
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| Main Authors: | , |
| Format: | research Journal Article |
| Published: |
Elsevier B.V.
Aug2019
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137431404&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137431404 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01909622 1ZF jtl: Journal of the American Academy of Dermatology issn: 01909622 maglogo: N pubinfo: dt: Aug2019 vid: 81 iid: 2 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 137431404 137431404 NLM30617027 137431404 10.1016/j.jaad.2018.10.029 NLM30617027 137431404 ppf: 527 ppct: 7 formats: tig: atl: Erosive pustular dermatosis of the scalp: A neutrophilic folliculitis within the spectrum of neutrophilic dermatoses: A clinicopathologic study of 30 cases. aug: au: Tomasini, Carlo Michelerio, Andrea affil: Department of Clinical-Surgical, Diagnostic, and Pediatric Science, Institute of Dermatology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy sug: subj: Neutrophils Pathology Skin Diseases Pathology Skin Diseases Diagnosis Folliculitis Pathology Diagnostic Errors Time Factors Aged, 80 and Over Female Middle Age Aged Alopecia Pathology Folliculitis Etiology Male Skin Diseases Etiology Human Aged, 80 & over Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Background: It is general opinion that histopathology is nonspecific and of little value in diagnosing erosive pustular dermatosis of the scalp (EPDS).Objectives: Clinicopathologic correlation of erosive pustular dermatosis of the scalp.Methods: We reviewed the clinical and pathologic records of patients with a clinicopathologic diagnosis of EPDS between 2011 and 2016 at the Dermatopathology Unit of Turin University.Results: Thirty elderly patients with EPDS were identified (22 men and 8 women). Androgenetic alopecia was present in 19 of 30 patients. Triggering factors included mechanical trauma in 10 of 30 cases, surgical procedures in 4 of 30 cases, and herpes zoster in 1 of 30 cases. Three patients were affected by autoimmune disorders. The vertex was the most common location. Disease presentation varied markedly from tiny, erosive, scaly lesions to crusted and hemorrhagic plaques, mimicking pustular pyoderma gangrenosum. The pathologic changes differed according to lesion type and disease duration. Interestingly, a spongiotic and suppurative infundibulo-folliculitis was observed in 8 of 30 cases.Limitations: This was a retrospective study.Conclusions: We believe that the primary lesion of erosive pustular dermatosis of the scalp is a spongiotic, pustular superficial folliculitis. The clinicopathologic similarities with other neutrophilic dermatoses, such as pustular pyoderma gangrenosum, suggest this condition should be included in this spectrum, where pathergy plays a pathogenetic role. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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