Delay discounting and reward sensitivity in a 2 × 2 study of bipolar disorder and alcohol dependence.
Background and Aims: Separate studies have shown increased delay discounting in people with bipolar disorder (BD) and people with alcohol dependence (AD) relative to people without mental health problems. Delay discounting was compared in people with no mental health problems, AD, BD and AD plus BD....
| Publicado en: | Addiction Vol. 114; no. 8; pp. 1369 - 1379 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137451111&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137451111 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Aug2019 vid: 114 iid: 8 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 137451111 137451111 137451111 10.1111/add.14625 137451111 ppf: 1369 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Delay discounting and reward sensitivity in a 2 × 2 study of bipolar disorder and alcohol dependence. aug: au: Mellick, William Tolliver, Bryan K. Brenner, Helena Prisciandaro, James J. affil: Department of Psychiatry and Behavioral Sciences, Addiction Sciences Division, Medical University of South Carolina, Charleston SC, USA sug: subj: Bipolar Disorder Alcoholism Delay Discounting Reward Human Male Female Adult Middle Age Factorial Design Comparative Studies Nonexperimental Studies Academic Medical Centers South Carolina South Carolina Self Report Questionnaires Univariate Statistics Bivariate Statistics Regression Impulsive Behavior Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background and Aims: Separate studies have shown increased delay discounting in people with bipolar disorder (BD) and people with alcohol dependence (AD) relative to people without mental health problems. Delay discounting was compared in people with no mental health problems, AD, BD and AD plus BD. Associations of delay discounting with self‐reported impulsivity and reward sensitivity were also assessed. Design: The study was a two‐by‐two factorial comparative observational design. Setting: Data were collected at baseline diagnostic visits as part of a neuroimaging study at a medical university in South Carolina, USA. Participants: Twenty‐two BD + AD, 33 BD, 28 AD and 27 people without mental health problems participated. Measurements Diagnostic and clinician‐rated symptom measures, self‐report questionnaires and a computerized delay discounting task were administered. Two‐by‐two general linear univariate models were tested to examine between‐group differences on discounting rates, and bivariate correlations and hierarchical regression analyses were performed to examine associations between discounting rates and self‐reported reward sensitivity and impulsivity. Findings There was a significant main effect of AD (P = 0.006, η2 = 0.068). The main effect of BD and the BD × AD interaction terms were non‐significant (P ≥ 0.293, η2 ≤ 0.010). Reward sensitivity and impulsivity were not significantly associated with discounting rates after adjustment for the other (P ≥ 0.089). Conclusions: People with alcohol dependence appear to have higher delay discounting, while previously found associations between bipolar disorder and delay discounting may be secondary to alcohol use disorder. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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