Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A).

Purpose: Synaptic abnormalities have been implicated in a variety of neuropsychiatric disorders, including epilepsy, Alzheimer's disease, and schizophrenia. Hence, PET imaging of the synaptic vesicle glycoprotein 2A (SV2A) may be a valuable in vivo biomarker for neurologic and psychiatric diseases....

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Bibliographic Details

Published in:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 46; no. 9; pp. 1952 - 1966
Main Authors:	Li, Songye, Cai, Zhengxin, Zhang, Wenjie, Holden, Daniel, Lin, Shu-fei, Finnema, Sjoerd J., Shirali, Anupama, Ropchan, Jim, Carre, Stephane, Mercier, Joel, Carson, Richard E., Nabulsi, Nabeel, Huang, Yiyun
Format:	Journal Article
Published:	Springer Nature Aug2019
Online Access:	View this record in EBSCOhost