Improved Deep Learning Network Based in combination with Cost-sensitive Learning for Early Detection of Ovarian Cancer in Color Ultrasound Detecting System.

With the development of theories and technologies in medical imaging, most of the tumors can be detected in the early stage. However, the nature of ovarian cysts lacks accurate judgement, leading to that many patients with benign nodules still need Fine Needle Aspiration (FNA) biopsies or surgeries,...

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Publicado en:Journal of Medical Systems Vol. 43; no. 8
Autores principales: Zhang, Lei, Huang, Jian, Liu, Li
Formato: equations & formulas review tables/charts Journal Article
Publicado: Springer Nature Aug2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2019
      vid: 43
      iid: 8
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-019-1356-8
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        atl: Improved Deep Learning Network Based in combination with Cost-sensitive Learning for Early Detection of Ovarian Cancer in Color Ultrasound Detecting System.
      aug:
        au:
          Zhang, Lei
          Huang, Jian
          Liu, Li
        affil: The Ultrasound Centre, Tianjin central hospital of gynecology obstetrics, 300052, Tianjin, China
      sug:
        subj:
          Ovarian Neoplasms Diagnosis
          Early Detection of Cancer Methods
          Ultrasonography, Doppler, Color Utilization
          Deep Learning
          Artificial Intelligence
          Costs and Cost Analysis
          Neural Networks (Computer)
          Diagnostic Imaging
          Biopsy, Needle Methods
          Health Care Costs
          Ovarian Neoplasms Mortality
          Biological Markers
          Magnetic Resonance Imaging
          Tomography, Emission-Computed
          Algorithms
          Tumor Markers, Biological
      ab: With the development of theories and technologies in medical imaging, most of the tumors can be detected in the early stage. However, the nature of ovarian cysts lacks accurate judgement, leading to that many patients with benign nodules still need Fine Needle Aspiration (FNA) biopsies or surgeries, increasing the physical pain and mental pressure of patients as well as unnecessary medical health care costs. Therefore, we present an image diagnosis system for classifying the ovarian cysts in color ultrasound images, which novelly applies the image features fused by both high-level features from deep learning network and low-level features from texture descriptor. Firstly, the ultrasound images are enhanced to improve the quality of training data set and the rotation invariant uniform local binary pattern (ULBP) features are extracted from each of the images as the low-level texture features. Then the high-level deep features extracted by the fine-tuned GoogLeNet neural network and the low-level ULBP features are normalized and cascaded as one fusion feature that can represent both the semantic context and the texture patterns distributed in the image. Finally, the fusion features are input to the Cost-sensitive Random Forest classifier to classify the images into "malignant" and "benign". The high-level features extracted by the deep neural network from the medical ultrasound image can reflect the visual features of the lesion region, while the low-level texture features can describe the edges, direction and distribution of intensities. Experimental results indicate that the combination of the two types of features can describe the differences between the lesion regions and other regions, and the differences between lesions regions of malignant and benign ovarian cysts.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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