Respiratory Sound Based Classification of Chronic Obstructive Pulmonary Disease: a Risk Stratification Approach in Machine Learning Paradigm.

This article investigates the classification of normal and COPD subjects on the basis of respiratory sound analysis using machine learning techniques. Thirty COPD and 25 healthy subject data are recorded. Total of 39 lung sound features and 3 spirometry features are extracted and evaluated. Various...

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Publicado en:Journal of Medical Systems Vol. 43; no. 8
Autores principales: Haider, Nishi Shahnaj, Singh, Bikesh Kumar, Periyasamy, R., Behera, Ajoy K.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Aug2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2019
      vid: 43
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-019-1388-0
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        atl: Respiratory Sound Based Classification of Chronic Obstructive Pulmonary Disease: a Risk Stratification Approach in Machine Learning Paradigm.
      aug:
        au:
          Haider, Nishi Shahnaj
          Singh, Bikesh Kumar
          Periyasamy, R.
          Behera, Ajoy K.
        affil: Biomedical, NIT Raipur, G E Road, 492010, Raipur, India
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive Diagnosis
          Respiratory Sounds
          Machine Learning Methods
          Risk Assessment
          Human
          Male
          Female
          Adult
          Middle Age
          India
          Spirometry
          Vital Capacity
          Logistic Regression
          Forced Expiratory Volume
          T-Tests
          Mann-Whitney U Test
          Spearman's Rank Correlation Coefficient
          Analysis of Variance
          Data Analysis Software
          ROC Curve
          Diffusion of Innovation
          Signal Processing, Computer Assisted
          Machinery
          Decision Trees
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: This article investigates the classification of normal and COPD subjects on the basis of respiratory sound analysis using machine learning techniques. Thirty COPD and 25 healthy subject data are recorded. Total of 39 lung sound features and 3 spirometry features are extracted and evaluated. Various parametric and nonparametric tests are conducted to evaluate the relevance of extracted features. Classifiers such as support vector machine (SVM), k-nearest neighbor (KNN), logistic regression (LR), decision tree and discriminant analysis (DA) are used to categorize normal and COPD breath sounds. Classification based on spirometry parameters as well as respiratory sound parameters are assessed. Maximum classification accuracy of 83.6% is achieved by the SVM classifier while using the most relevant lung sound parameters i.e. median frequency and linear predictive coefficients. Further, SVM classifier and LR classifier achieved classification accuracy of 100% when relevant lung sound parameters, i.e. median frequency and linear predictive coefficient are combined with the spirometry parameters, i.e. forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1). It is concluded that combining lung sound based features with spirometry data can improve the accuracy of COPD diagnosis and hence the clinician's performance in routine clinical practice. The proposed approach is of great significance in a clinical scenario wherein it can be used to assist clinicians for automated COPD diagnosis. A complete handheld medical system can be developed in the future incorporating lung sounds for COPD diagnosis using machine learning techniques.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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