Spectral Analysis of Codons in the DNA Sequence of Fragile X Syndrome.

There are frequent studies undergoing related to the Fragile X syndrome caused due to the triplet CGG replicates on the X chromosome of Fragile X Mental Retardation 1 (FMR1) gene. Mutations of this chromosome can lead to Fragile X syndrome, rational disability, and other cognitive discrepancies. A n...

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Publicado en:Journal of Medical Systems Vol. 43; no. 8
Autores principales: S, Jeya Bharathi, P, Balamanikandan
Formato: equations & formulas tables/charts Journal Article
Publicado: Springer Nature Aug2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2019
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-019-1408-0
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        atl: Spectral Analysis of Codons in the DNA Sequence of Fragile X Syndrome.
      aug:
        au:
          S, Jeya Bharathi
          P, Balamanikandan
        affil: Department of Mathematics, Thiagarajar College of Engineering, Madurai, Tamil Nadu, India
      sug:
        subj:
          Spectral Analysis
          Genes
          DNA
          Fragile X Syndrome Therapy
          Mutation
          Proteins
          Intellectual Disability
          Health Behavior
          Connective Tissue Abnormalities
          Phenotype
          Alleles
          Sequence Analysis
          Recovery
          Early Diagnosis
      ab: There are frequent studies undergoing related to the Fragile X syndrome caused due to the triplet CGG replicates on the X chromosome of Fragile X Mental Retardation 1 (FMR1) gene. Mutations of this chromosome can lead to Fragile X syndrome, rational disability, and other cognitive discrepancies. A novel approach based on Rajan Transform is proposed to analyze the spectral density of codons. The traditional transform like Fourier transform provides imaginary values whereas the Rajan Transform exhibits only the real values. The mutations there in the DNA are successfully distinguished by using the Rajan Transform which is suitable tool for the spectral analysis of DNA sequences. The utilization of the Rajan Transform urges larger profits in terms of minimal false alarm rate and thereby leading to an increase in the accuracy of the spectral analysis.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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