Encoding the local connectivity patterns of fMRI for cognitive task and state classification.

In this work, we propose a novel framework to encode the local connectivity patterns of brain, using Fisher vectors (FV), vector of locally aggregated descriptors (VLAD) and bag-of-words (BoW) methods. We first obtain local descriptors, called mesh arc descriptors (MADs) from fMRI data, by forming l...

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Publicado en:Brain Imaging & Behavior Vol. 13; no. 4; pp. 893 - 905
Autores principales: Onal Ertugrul, Itir, Ozay, Mete, Yarman Vural, Fatos T.
Formato: Journal Article
Publicado: Springer Nature Aug2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2019
      vid: 13
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      pub: Springer Nature
      place: New York, New York
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        atl: Encoding the local connectivity patterns of fMRI for cognitive task and state classification.
      aug:
        au:
          Onal Ertugrul, Itir
          Ozay, Mete
          Yarman Vural, Fatos T.
        affil: Robotics Institute, Carnegie Mellon University, Pittsburgh, PA, USA
      sug:
        subj:
          Information Science Methods
          Brain Mapping Methods
          Nervous System
          Magnetic Resonance Imaging Methods
          Models, Theoretical
          Cluster Analysis
          Cognition
          Statistics
          Brain Physiology
          Brain
          Scales
      ab: In this work, we propose a novel framework to encode the local connectivity patterns of brain, using Fisher vectors (FV), vector of locally aggregated descriptors (VLAD) and bag-of-words (BoW) methods. We first obtain local descriptors, called mesh arc descriptors (MADs) from fMRI data, by forming local meshes around anatomical regions, and estimating their relationship within a neighborhood. Then, we extract a dictionary of relationships, called brain connectivity dictionary by fitting a generative Gaussian mixture model (GMM) to a set of MADs, and selecting codewords at the mean of each component of the mixture. Codewords represent connectivity patterns among anatomical regions. We also encode MADs by VLAD and BoW methods using k-Means clustering. We classify cognitive tasks using the Human Connectome Project (HCP) task fMRI dataset and cognitive states using the Emotional Memory Retrieval (EMR). We train support vector machines (SVMs) using the encoded MADs. Results demonstrate that, FV encoding of MADs can be successfully employed for classification of cognitive tasks, and outperform VLAD and BoW representations. Moreover, we identify the significant Gaussians in mixture models by computing energy of their corresponding FV parts, and analyze their effect on classification accuracy. Finally, we suggest a new method to visualize the codewords of the learned brain connectivity dictionary.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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