Abnormal neural responses to emotional stimuli in children with primary monosymptomatic nocturnal enuresis.
Nocturnal enuresis (NE) is a common disorder in school-aged children that has been reported to affect nearly 10% of 7-year-old children and affects both the children and their families. Previous studies have shown that the risk of psychosocial difficulties in children with enuresis is elevated. Thus...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 28; no. 7; pp. 949 - 957 |
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| Autores principales: | , , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jul2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137558640&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137558640 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Jul2019 vid: 28 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 137558640 137558640 137558640 10.1007/s00787-018-1255-4 137558640 ppf: 949 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Abnormal neural responses to emotional stimuli in children with primary monosymptomatic nocturnal enuresis. aug: au: Wang, Mengxing Zhang, Anyi Qin, Zhaoxia Xu, Shuai Ban, Shiyu Zhang, Jilei Ma, Jun Du, Xiaoxia affil: Shanghai Key Laboratory of Magnetic Resonance and Department of Physics, School of Physics and Materials Science, East China Normal University, 3663 North Zhong-Shan Road, 200062, Shanghai, People's Republic of China sug: subj: Enuresis, Nocturnal Psychosocial Factors Emotions Evaluation Evoked Potentials Evaluation Diagnosis, Brain Methods Magnetic Resonance Imaging Methods Affective Disorders Risk Factors Task Performance and Analysis Human Frontal Lobe Physiology Limbic System Physiology Child Neural Pathways Motion Pictures Child: 6-12 years ab: Nocturnal enuresis (NE) is a common disorder in school-aged children that has been reported to affect nearly 10% of 7-year-old children and affects both the children and their families. Previous studies have shown that the risk of psychosocial difficulties in children with enuresis is elevated. Thus, children with NE may experience negative effects on psychosocial health or emotion processing. Therefore, the aim of this study was to investigate the potential disturbance in emotional processing in children with NE using functional magnetic resonance imaging (fMRI). In this work, we used fMRI and an affective picture task to evaluate brain response changes in children with NE. Two groups, one consisting of 22 children with primary monosymptomatic NE and one with 23 healthy controls, were scanned using fMRI. Compared to the healthy subjects, children with NE mainly showed increased activation when viewing negative vs. neutral pictures in the bilateral medial superior frontal gyrus that extended to the anterior cingulate cortex. Our results demonstrated that children with primary monosymptomatic NE showed abnormal neural responses to emotional stimuli and overactivation in the medial prefrontal and anterior cingulate cortices suggested that children with primary monosymptomatic NE may be hypersensitive in their sensory perception of negative pictures. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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