Exploring the approximate number system in Sotos syndrome: insights from a dot comparison task.

Background: Sotos syndrome is a congenital overgrowth condition associated with intellectual disability and an uneven cognitive profile. Previous research has established that individuals with Sotos syndrome have relatively poor mathematical ability, but domain‐specific numeracy skills have not been...

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Published in:Journal of Intellectual Disability Research Vol. 63; no. 8; pp. 917 - 926
Main Authors: Lane, C., Van Herwegen, J., Freeth, M.
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Aug2019
Online Access:View this record in EBSCOhost
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    uiTerm: 137586043
    longDbName: CINAHL Complete
    uiTag: AN
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      dt: Aug2019
      vid: 63
      iid: 8
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jir.12604
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        atl: Exploring the approximate number system in Sotos syndrome: insights from a dot comparison task.
      aug:
        au:
          Lane, C.
          Van Herwegen, J.
          Freeth, M.
        affil: Department of Psychology, The University of Sheffield, Sheffield UK
      sug:
        subj:
          Sotos' Syndrome Diagnosis
          Mathematics Evaluation
          Executive Function Evaluation
          Task Performance and Analysis
          Adolescent Health
          Human
          Adolescence
          Age Factors
          Williams Syndrome Diagnosis
          Sotos' Syndrome Complications
          Cognition Disorders Risk Factors
          Adolescent: 13-18 years
      ab: Background: Sotos syndrome is a congenital overgrowth condition associated with intellectual disability and an uneven cognitive profile. Previous research has established that individuals with Sotos syndrome have relatively poor mathematical ability, but domain‐specific numeracy skills have not been explored within this population. This study investigated the approximate number system (ANS) in Sotos syndrome. Method: A dot comparison task was administered to 20 participants with Sotos syndrome (mean age in years = 18.43, SD = 9.29). Performance was compared to a chronological agematched typically developing control group (n = 25) and a mental age‐matched Williams syndrome group (n = 24). Results: The Sotos group did not display an ANS deficit overall when compared to chronological agematched control participants. However, for trials where the size of the individual dots and the envelope area were negatively correlated with the total number of dots (incongruent trials), the Sotos group were less accurate than the typically developing group but more accurate than the Williams syndrome group, suggesting an inhibitory control deficit. Better accuracy on incongruent trials, but not congruent trials, was associated with higher quantitative reasoning ability for participants with Sotos syndrome. Conclusion: Overall, the findings suggest that ANS acuity is not impaired in Sotos syndrome but that numerical difficulties may be associated with an inhibitory control deficit for individuals with Sotos syndrome.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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