Food groups and risk of age-related macular degeneration: a systematic review with meta-analysis.

Objective: To systematically review all the available evidence from prospective cohort studies that investigated the association between consumption of food groups and the occurrence of age-related macular degeneration (AMD). Methods: We conducted an electronic literature search through MedLine, Emb...

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Publicado en:European Journal of Nutrition Vol. 58; no. 5; pp. 2123 - 2144
Autores principales: Dinu, Monica, Pagliai, Giuditta, Casini, Alessandro, Sofi, Francesco
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Springer Nature Aug2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2019
      vid: 58
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00394-018-1771-5
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        atl: Food groups and risk of age-related macular degeneration: a systematic review with meta-analysis.
      aug:
        au:
          Dinu, Monica
          Pagliai, Giuditta
          Casini, Alessandro
          Sofi, Francesco
        affil: Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy
      sug:
        subj:
          Food Intake Evaluation
          Macular Degeneration Risk Factors
          Risk Assessment
          Human
          Systematic Review
          Meta Analysis
          Medline
          Embase
          Vegetables
          Fruit
          Nuts
          Cereals
          Dairy Products
          Dietary Fats
          Oils
          Butter
          Margarine
          Fish
          Macular Degeneration Prevention and Control
          Relative Risk
          Confidence Intervals
          Meat
          Binge Drinking Complications
      ab: Objective: To systematically review all the available evidence from prospective cohort studies that investigated the association between consumption of food groups and the occurrence of age-related macular degeneration (AMD). Methods: We conducted an electronic literature search through MedLine, Embase, Google Scholar, Web of Science, and bibliographies of retrieved articles up to January, 2018. Studies were included if they analysed prospectively the association between consumption of food groups and AMD. Results: At the end of the selection process, 26 articles were included in the meta-analysis, for a total of 211,676 subjects and 7154 cases of AMD. By comparing the highest vs. the lowest consumption, pooled analyses showed no significant association with AMD for vegetables, fruit, nuts, grains, dairy products, as well as dietary fats such as oils, butter and margarine. Fish determined a significant (p < 0.05) reduction of risk for total AMD (RR 0.82 95% CI 0.75–0.90), as well as for both early (RR 0.84 95% CI 0.73–0.97), and late (RR 0.79 95% CI 0.70–0.90) AMD. On the other hand, high meat consumption was associated with a significant increased risk of early (RR 1.17 95% CI 1.02–1.34), but not late AMD. Finally, a significant increased risk of AMD for the highest consumption of alcohol (RR 1.20 95% CI 1.04–1.39) was reported. Conclusions: The results of the present meta-analysis show a significant 18% reduced risk for fish and a 20% increased risk for alcohol consumption. In addition, an increased risk was observed for meat, but only in the subgroup of early AMD.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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