Motor-Induced Suppression of the N100 Event-Related Potential During Motor Imagery Control of a Speech Synthesizer Brain-Computer Interface.

Purpose: Speech motor control relies on neural processes for generating sensory expectations using an efference copy mechanism to maintain accurate productions. The N100 auditory event-related potential (ERP) has been identified as a possible neural marker of the efference copy with a reduced amplit...

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Publicado en:Journal of Speech, Language & Hearing Research Vol. 62; no. 7; pp. 2133 - 2141
Autores principales: Brumberg, Jonathan S., Pitt, Kevin M.
Formato: Artículo
Publicado: American Speech-Language-Hearing Association Jul2019
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2019
      vid: 62
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      pub: American Speech-Language-Hearing Association
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        137617089
        10.1044/2019_JSLHR-S-MSC18-18-0198
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        atl: Motor-Induced Suppression of the N100 Event-Related Potential During Motor Imagery Control of a Speech Synthesizer Brain-Computer Interface.
      aug:
        au:
          Brumberg, Jonathan S.
          Pitt, Kevin M.
        affil: Department of Speech-Language-Hearing: Sciences & Disorders, The University of Kansas, Lawrence
      su:
        Motor ability
        Mental imagery
        Communication devices for people with disabilities
        Physiological aspects of speech
        Vocoder
        Brain physiology
        Auditory evoked response
        Electroencephalography
        Listening
        Brain-computer interfaces
      sug:
        subj:
          Motor ability
          Mental imagery
          Communication devices for people with disabilities
          Physiological aspects of speech
          Vocoder
          Brain physiology
          Auditory evoked response
          Electroencephalography
          Listening
          Brain-computer interfaces
      ab: Purpose: Speech motor control relies on neural processes for generating sensory expectations using an efference copy mechanism to maintain accurate productions. The N100 auditory event-related potential (ERP) has been identified as a possible neural marker of the efference copy with a reduced amplitude during active listening while speaking when compared to passive listening. This study investigates N100 suppression while controlling a motor imagery speech synthesizer brain-computer interface (BCI) with instantaneous auditory feedback to determine whether similar mechanisms are used for monitoring BCI-based speech output that may both support BCI learning through existing speech motor networks and be used as a clinical marker for the speech network integrity in individuals without severe speech and physical impairments. Method: The motor-induced N100 suppression is examined based on data from 10 participants who controlled a BCI speech synthesizer using limb motor imagery. We considered listening to auditory target stimuli (without motor imagery) in the BCI study as passive listening and listening to BCI-controlled speech output (with motor imagery) as active listening since audio output depends on imagined movements. The resulting ERP was assessed for statistical significance using a mixed-effects general linear model. Results: Statistically significant N100 ERP amplitude differences were observed between active and passive listening during the BCI task. Post hoc analyses confirm the N100 amplitude was suppressed during active listening. Conclusion: Observation of the N100 suppression suggests motor planning brain networks are active as participants control the BCI synthesizer, which may aid speech BCI mastery.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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