End stage scurvy in the developed world: A diagnostic conundrum but not to be mistaken for pyoderma gangrenosum.

Scurvy is a clinical syndrome, resulting from ascorbic acid deficiency. Prevalence of the condition is now extremely low in the Western population and its diagnosis can be challenging without a high index of suspicion. When cases do present, they are often misdiagnosed initially. Therefore, a thorou...

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Publicado en:International Wound Journal Vol. 16; no. 4; pp. 1024 - 1029
Autores principales: Le, Stephanie T., Wang, Jenny Z., Alexanian, Claire C., Johng, Stephanie Y., Patel, Forum B., Wang, Elizabeth A., Ma, Chelsea, Wilken, Reason, Cheng, Michelle Y., Maverakis, Emanual
Formato: case study pictorial Journal Article
Publicado: Wiley-Blackwell Aug2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2019
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: End stage scurvy in the developed world: A diagnostic conundrum but not to be mistaken for pyoderma gangrenosum.
      aug:
        au:
          Le, Stephanie T.
          Wang, Jenny Z.
          Alexanian, Claire C.
          Johng, Stephanie Y.
          Patel, Forum B.
          Wang, Elizabeth A.
          Ma, Chelsea
          Wilken, Reason
          Cheng, Michelle Y.
          Maverakis, Emanual
        affil: Department of Dermatology, University of California, Davis, Sacramento California
      sug:
        subj:
          Developed Countries
          Scurvy Diagnosis
          Scurvy Classification
          Diagnostic Errors
          Pyoderma Gangrenosum
          Leg Ulcer
          Scurvy Therapy
          Hormone Replacement Therapy
          Incidence
          Nutritional Support
          Wound Healing
      ab: Scurvy is a clinical syndrome, resulting from ascorbic acid deficiency. Prevalence of the condition is now extremely low in the Western population and its diagnosis can be challenging without a high index of suspicion. When cases do present, they are often misdiagnosed initially. Therefore, a thorough history, physical exam, and laboratory evaluation are key to showing this now rare but extremely well‐known disease. We report a case of scurvy manifesting as persistent non‐healing lower‐extremity ulcerations, initially mistaken for pyoderma gangrenosum. The patient responded to appropriate replacement therapy, but ulcers were slow to heal. As was the case in our patient, symptom reversal may require additional nutritional replacement. We encourage physicians to consider nutritional deficiencies in their differential diagnoses and highlight the incidence of malnutrition in the proper clinical setting to avoid diagnostic delay.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
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