Reduction of False-Positive Markings on Mammograms: a Retrospective Comparison Study Using an Artificial Intelligence-Based CAD.

The aim was to determine whether an artificial intelligence (AI)-based, computer-aided detection (CAD) software can be used to reduce false positive per image (FPPI) on mammograms as compared to an FDA-approved conventional CAD. A retrospective study was performed on a set of 250 full-field digital...

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Published in:Journal of Digital Imaging Vol. 32; no. 4; pp. 618 - 625
Main Authors: Mayo, Ray Cody, Kent, Daniel, Sen, Lauren Chang, Kapoor, Megha, Leung, Jessica W. T., Watanabe, Alyssa T.
Format: diagnostic images research tables/charts Journal Article
Published: Springer Nature Aug2019
Online Access:View this record in EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-018-0168-6
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        atl: Reduction of False-Positive Markings on Mammograms: a Retrospective Comparison Study Using an Artificial Intelligence-Based CAD.
      aug:
        au:
          Mayo, Ray Cody
          Kent, Daniel
          Sen, Lauren Chang
          Kapoor, Megha
          Leung, Jessica W. T.
          Watanabe, Alyssa T.
        affil: Department of Diagnostic Imaging, Breast Imaging Division, MD Anderson Center, University of Texas, 1515 Holcombe Blvd., 77030, Houston, TX, USA
      sug:
        subj:
          Mammography
          False Positive Results
          Diagnostic Errors Prevention and Control
          Artificial Intelligence Utilization
          Image Interpretation, Computer Assisted Methods
          Human
          Retrospective Design
          Comparative Studies
          Sensitivity and Specificity
          Cancer Screening Methods
          Descriptive Statistics
          Confidence Intervals
          Calcinosis
          Diagnosis, Computer Assisted
      ab: The aim was to determine whether an artificial intelligence (AI)-based, computer-aided detection (CAD) software can be used to reduce false positive per image (FPPI) on mammograms as compared to an FDA-approved conventional CAD. A retrospective study was performed on a set of 250 full-field digital mammograms between January 1, 2013, and March 31, 2013, and the number of marked regions of interest of two different systems was compared for sensitivity and specificity in cancer detection. The count of false-positive marks per image (FPPI) of the two systems was also evaluated as well as the number of cases that were completely mark-free. All results showed statistically significant reductions in false marks with the use of AI-CAD vs CAD (confidence interval = 95%) with no reduction in sensitivity. There is an overall 69% reduction in FPPI using the AI-based CAD as compared to CAD, consisting of 83% reduction in FPPI for calcifications and 56% reduction for masses. Almost half (48%) of cases showed no AI-CAD markings while only 17% show no conventional CAD marks. There was a significant reduction in FPPI with AI-CAD as compared to CAD for both masses and calcifications at all tissue densities. A 69% decrease in FPPI could result in a 17% decrease in radiologist reading time per case based on prior literature of CAD reading times. Additionally, decreasing false-positive recalls in screening mammography has many direct social and economic benefits.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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