A Systematic Review and Meta-analysis of Antiretroviral Therapy (ART) Adherence Interventions for Women Living with HIV.
A systematic review and meta-analysis was conducted to determine the efficacy of women-focused ART adherence interventions. Included studies (a) reported on a behavioral ART adherence intervention for cis-women living with HIV, (b) measured ART adherence as an outcome, and (c) employed a randomized...
| Publicado en: | AIDS & Behavior Vol. 23; no. 8; pp. 1998 - 2014 |
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| Autores principales: | , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Aug2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137642051&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137642051 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: Aug2019 vid: 23 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 137642051 137642051 137642051 10.1007/s10461-018-2341-9 137642051 ppf: 1998 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A Systematic Review and Meta-analysis of Antiretroviral Therapy (ART) Adherence Interventions for Women Living with HIV. aug: au: Pellowski, Jennifer A. Price, Devon M. Harrison, Abigail D. Tuthill, Emily L. Myer, Landon Operario, Don Lurie, Mark N. affil: Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA sug: subj: HIV Infections Drug Therapy Anti-Retroviral Agents Therapeutic Use Medication Compliance Outcome Assessment Women's Health Human Systematic Review Meta Analysis HIV-Positive Persons Psychosocial Factors Program Evaluation ab: A systematic review and meta-analysis was conducted to determine the efficacy of women-focused ART adherence interventions. Included studies (a) reported on a behavioral ART adherence intervention for cis-women living with HIV, (b) measured ART adherence as an outcome, and (c) employed a randomized controlled trial design. Thirteen studies were included in the meta-analysis. Overall, interventions significantly improved ART adherence compared to control conditions (random-effects d = 0.82, 95% CI [0.18, 1.45], p = 0.01), however, this was largely driven by two studies that had effect sizes greater than 3 standard errors above the mean effect size. Key moderators were location, recruitment method, group-based intervention, and alteration of the healthcare system. Innovative behavioral interventions that focus on young women and adolescents, target the critical periods of pregnancy and postpartum and test the integration of multiple levels of intervention to create lasting effects on ART adherence are needed. Resumen: Se llevó a cabo una revisión sistemática y un metaanálisis para determinar la eficacia de las intervenciones de adherencia al tratamiento antirretroviral (TAR) centradas en las mujeres. Los estudios incluidos (a) informaron sobre una intervención conductual de adherencia a TAR para mujeres cisgénero que viven con VIH, (b) midieron la adherencia a TAR como resultado y (c) emplearon un diseño de ensayo controlado aleatorio. Se incluyeron trece estudios en el metaanálisis. En general, las intervenciones mejoraron significativamente la adherencia al tratamiento de TAR en comparación con las condiciones de control (efectos aleatorios d = 0,84, IC del 95% [0,21, 1,47], p = 0,01), sin embargo, esto se debió principalmente a dos estudios que tuvieron tamaños de efectos superiores a 3 errores estándares por encima del tamaño medio del efecto. Los moderadores clave fueron la ubicación, el método de reclutamiento, la intervención grupal y la alteración del sistema de salud. Se necesitan intervenciones innovadoras de comportamiento que se enfoquen en mujeres jóvenes y adolescentes, que se centren en los períodos críticos del embarazo y el posparto y que prueben la integración de múltiples niveles de intervención para crear efectos duraderos en la adherencia al tratamiento antirretroviral. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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