Poststreptococcal acute glomerulonephritis: fact and controversy.
Poststreptococcal acute glomerulonephritis is prototypic of the immunologic glomerulonephritides. It most commonly follows streptococcal infection of the pharynx or skin. The diagnosis is usually not difficult when a nephritic clinical presentation (with such manifestations as hematuria, edema, and...
| Publicado en: | Annals of Internal Medicine Vol. 91; no. 1; pp. 76 - 87 |
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| Autores principales: | , , , |
| Formato: | research review Journal Article |
| Publicado: |
American College of Physicians
Jul79
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137743276&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137743276 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00034819 AIM jtl: Annals of Internal Medicine issn: 00034819 maglogo: N pubinfo: dt: Jul79 vid: 91 iid: 1 pid: 1652 pub: American College of Physicians place: Philadelphia, Pennsylvania artinfo: ui: 137743276 137743276 NLM380430 137743276 10.7326/0003-4819-91-1-76 NLM380430 137743276 ppf: 76 ppct: 11 formats: tig: atl: Poststreptococcal acute glomerulonephritis: fact and controversy. aug: au: Nissenson, A R Baraff, L J Fine, R N Knutson, D W sug: subj: Streptococcal Infections Immunology Streptococcal Infections Microbiology Glomerulonephritis Etiology Pyoderma Diagnosis Kidney Failure, Chronic Etiology Child, Preschool Glomerulonephritis Complications Adolescence Acute Disease Glomerulonephritis Immunology Antigens Diagnosis, Differential Pharyngitis Diagnosis Human Glomerulonephritis Diagnosis Child Rheumatic Fever Etiology Validation Studies Comparative Studies Evaluation Research Multicenter Studies Clinical Assessment Tools Scales Child, Preschool: 2-5 years Adolescent: 13-18 years Child: 6-12 years ab: Poststreptococcal acute glomerulonephritis is prototypic of the immunologic glomerulonephritides. It most commonly follows streptococcal infection of the pharynx or skin. The diagnosis is usually not difficult when a nephritic clinical presentation (with such manifestations as hematuria, edema, and hypertension) is associated with serologic evidence of recent streptococcal infection and a depressed serum complement concentration. Currently, however, the nephritogenic antigen(s) has not been identified and has not been shown to be the same antigen for all nephritogenic streptococci; it may not even be a part of the infecting organism. The development of a vaccine to prevent this illness from occurring is therefore still not possible. Whether poststreptococcal acute glomerulonephritis progresses to chronic renal failure is still uncertain. Painstaking laboratory research together with careful, prospective long-term follow-up studies of patients with poststreptococcal acute glomerulonephritis may provide some of the answers to these critical questions. pubtype: Academic Journal doctype: research review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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