Unidentified gram-negative rod infection. A new disease of man.
A Gram-negative bacillus that defies identification was isolated from blood cultures of 17 patients with fever. Fifteen patients were male adults, and 14 patients had underlying diseases, including previous splenectomy in five, which impair host defenses against infection. Illnesses occurred in the...
| Published in: | Annals of Internal Medicine Vol. 86; no. 1; pp. 1 - 6 |
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| Main Authors: | , , , , , , |
| Format: | research Journal Article |
| Published: |
American College of Physicians
Jan77
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137743490&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137743490 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00034819 AIM jtl: Annals of Internal Medicine issn: 00034819 maglogo: N pubinfo: dt: Jan77 vid: 86 iid: 1 pid: 1652 pub: American College of Physicians place: Philadelphia, Pennsylvania artinfo: ui: 137743490 137743490 NLM835907 137743490 10.7326/0003-4819-86-1-1 NLM835907 137743490 ppf: 1 ppct: 5 formats: tig: atl: Unidentified gram-negative rod infection. A new disease of man. aug: au: Butler, T Weaver, R E Ramani, T K Uyeda, C T Bobo, R A Ryu, J S Kohler, R B sug: subj: Bacterial Infections Microbiology Bacteria Endocarditis, Bacterial Microbiology Animal Studies Adult Bacterial Infections Etiology Sepsis Microbiology Public Health Adolescence Bacteria Classification Aged Autopsy Splenectomy Human Middle Age Bites and Stings Complications Male Dogs Female Cellulitis Microbiology Validation Studies Comparative Studies Evaluation Research Multicenter Studies Center for Epidemiological Studies Depression Scale Adult: 19-44 years Adolescent: 13-18 years Aged: 65+ years Middle Aged: 45-64 years Male Female ab: A Gram-negative bacillus that defies identification was isolated from blood cultures of 17 patients with fever. Fifteen patients were male adults, and 14 patients had underlying diseases, including previous splenectomy in five, which impair host defenses against infection. Illnesses occurred in the summer and autumn in 14 cases and had been recently preceded by dog bites in 10 cases. Clincal syndromes included cellulitis in seven cases, primary bacteremia without localization in four, purulent meningitis in four, and endocarditis in three. Three patients died. The organism grows slowly on blood or chocolate agar in 10% CO, is oxidase- and catalase-positive, and is negative for nitrate reduction, indole production, and urease. It produces acid from glucose, lactose, and maltose. These features distinguish it from all previously described and classified bacteria. Furthermore, the epidemiologic features of the patients suggest that this organism is an opportunistic invader and may have an animal reservoir in nature. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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