The clinical significance of Campylobacter pylori.

Campylobacter pylori has recently been isolated from gastric mucosal biopsy specimens. Campylobacter pylori has many attributes in common with other campylobacters but it may represent a new genus. It produces abundant quantities of urease, and this property has been used to develop a rapid diagnost...

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Publicado en:Annals of Internal Medicine Vol. 108; no. 1; pp. 70 - 80
Autores principales: Dooley, C P, Cohen, H
Formato: Journal Article
Publicado: American College of Physicians Jan88
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan88
      vid: 108
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      pub: American College of Physicians
      place: Philadelphia, Pennsylvania
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        atl: The clinical significance of Campylobacter pylori.
      aug:
        au:
          Dooley, C P
          Cohen, H
        affil: Department of Medicine, LAC-USC Medical Center, USC School of Medicine
      sug:
        subj:
          Gastric Mucosa Microbiology
          Campylobacter
          Campylobacter Infections
          Peptic Ulcer Complications
          Gastritis Complications
          Duodenal Ulcer Complications
          Animals
          Dyspepsia Etiology
          Gastroesophageal Reflux Etiology
          Campylobacter Classification
          Gastritis Etiology
          Stomach Neoplasms Etiology
          Peptic Ulcer Etiology
      ab: Campylobacter pylori has recently been isolated from gastric mucosal biopsy specimens. Campylobacter pylori has many attributes in common with other campylobacters but it may represent a new genus. It produces abundant quantities of urease, and this property has been used to develop a rapid diagnostic test. The organism is found predominantly beneath the gastric mucus layer that lines the surface epithelium of the stomach. Infection with C. pylori causes an acute histologic gastritis which may become chronic. The bacterium is the etiologic agent in type-B gastritis. Prevalence of the organism in asymptomatic persons appears to be age related. Campylobacter pylori is found commonly in patients with peptic ulcer disease, always in association with chronic gastritis. Eradication of the organism is associated with healing of the gastritis and a lower relapse rate in duodenal ulcer disease. A role for the organism in other upper gastrointestinal diseases is unproven.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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