Dermatologic Urgencies and Emergencies: What Every Pathologist Should Know.

* Context.--Fatal dermatologic diseases and ones with high morbidity can occur in the inpatient setting. In such cases, prompt and accurate assessment of a bedside skin biopsy is required. This may be challenging for many pathologists who are not familiar with the complexity of skin pathology and sk...

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Published in:Archives of Pathology & Laboratory Medicine Vol. 143; no. 8; pp. 919 - 943
Main Authors: Abate, Mallory S., Battle, Laura R., Emerson, Ashley N., Gardner, Jerad M., Shalin, Sara C.
Format: pictorial review Journal Article
Published: College of American Pathologists Aug2019
Online Access:View this record in EBSCOhost
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      dt: Aug2019
      vid: 143
      iid: 8
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      pub: College of American Pathologists
      place: Northfield, Illinois
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        atl: Dermatologic Urgencies and Emergencies: What Every Pathologist Should Know.
      aug:
        au:
          Abate, Mallory S.
          Battle, Laura R.
          Emerson, Ashley N.
          Gardner, Jerad M.
          Shalin, Sara C.
        affil: Department of Dermatology, Saint Louis University, St Louis, Missouri
      sug:
        subj:
          Mycoses Diagnosis
          Stevens-Johnson Syndrome Diagnosis
          Epidermal Necrolysis, Toxic Diagnosis
          Staphylococcal Scalded Skin Syndrome Diagnosis
          Graft Versus Host Disease Diagnosis
          Pemphigoid, Bullous Diagnosis
          Calciphylaxis Diagnosis
          Sweet's Syndrome
          Pyoderma Gangrenosum
          Vasculitis
          Peer Review
          Life Experiences
          Cell Transplantation
          Collaboration
          Dermatology
          Patient Care
          Communication
          Dermatologists
      ab: * Context.--Fatal dermatologic diseases and ones with high morbidity can occur in the inpatient setting. In such cases, prompt and accurate assessment of a bedside skin biopsy is required. This may be challenging for many pathologists who are not familiar with the complexity of skin pathology and skin terminology within the fields of dermatopathology and dermatology. Objective.--To provide the pathologist with a practical, up-to-date, and "must-know" reference guide on dermatologic urgencies and emergencies from a real-world perspective, highlighting diagnostic pearls, diagnostic pitfalls, and commonly encountered practice gaps. This review will focus on key diseases with which every pathologist should be familiar, including angioinvasive fungal infections, Stevens-Johnson syndrome/toxic epidermal necrolysis, staph-scalded-skin syndrome, acute graftversus- host disease, bullous pemphigoid, calciphylaxis, Sweet syndrome and its histiocytoid variant, pyoderma gangrenosum, and leukocytoclastic vasculitis, as well as those in their clinical and histopathologic differential. Data Sources.--This review is based on peer-reviewed literature and our personal experiences with these diseases at major academic institutions, including one where a large number of stem cell transplants are performed. This review is unique as it represents collaborative expert opinion from both a dermatopathology and a dermatology standpoint. Conclusions.--This review outlines the critical role that the pathologist plays in the outcomes of patients with dermatologic urgencies and emergencies. Improved patient care will result from prompt and accurate histopathologic diagnoses as well as an open line of communication with the dermatologist.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        Journal Article
      ougenre: Article
    language: English
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