Perilipin5 protects against lipotoxicity and alleviates endoplasmic reticulum stress in pancreatic β-cells.

Background: Chronic exposure of pancreatic β-cells to excess free fatty acids is thought to contribute to type 2 diabetes pathogenesis in obesity by impairing β-cell function and even leading to apoptosis. In β-cells, lipid droplet-associated protein perilipin 5 (PLIN5) has been shown to enhance ins...

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Bibliographic Details

Published in:	Nutrition & Metabolism Vol. 16; no. 1
Main Authors:	Zhu, Yunxia, Zhang, Xiaoyan, Zhang, Li, Zhang, Mingliang, Li, Ling, Luo, Deng, Zhong, Yuan
Format:	research tables/charts Journal Article
Published:	BioMed Central 7/30/2019
Online Access:	View this record in EBSCOhost