Sodium valproate in psychiatric practice: time for a change in perception.
SummarySodium valproate and related preparations have recently undergone regulatory review following concern about effects on the unborn child and doctors' failure to communicate risk. The issues are wider. Valproate is overused in psychiatry based on the false perception that 'ease' of use equates...
| Publicado en: | British Journal of Psychiatry Vol. 215; no. 3; pp. 516 - 519 |
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| Formato: | Journal Article |
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Cambridge University Press
Sep2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137971919&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137971919 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00071250 1V6 jtl: British Journal of Psychiatry issn: 00071250 maglogo: N pubinfo: dt: Sep2019 vid: 215 iid: 3 pid: 15979 pub: Cambridge University Press artinfo: ui: 137971919 137971919 NLM31190658 10.1192/bjp.2019.137 NLM31190658 137971919 ppf: 516 ppct: 3 formats: tig: atl: Sodium valproate in psychiatric practice: time for a change in perception. aug: au: Owens, David Cunningham affil: Professor of Clinical Psychiatry and Honorary Consultant Psychiatrist, Centre for Clinical Brain Sciences, Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK. sug: ab: SummarySodium valproate and related preparations have recently undergone regulatory review following concern about effects on the unborn child and doctors' failure to communicate risk. The issues are wider. Valproate is overused in psychiatry based on the false perception that 'ease' of use equates to better safety than alternatives. Valproic acid can disrupt fundamental physiological processes, the consequences of which are poorly understood and little discussed in the psychiatric literature. Valproate may be useful in a small number of patients with bipolar disorder but current prescribing patterns are unjustified. Perception needs to change.Declaration of interestD.C.O. is psychiatric commissioner on the Commission on Human Medicines and a member of the European Medicines Agency's Scientific Advisory Group on Psychiatry. He chaired the European Medicines Agency's review of the psychiatric use of valproate in pregnancy and women of childbearing potential. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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