Subgroup identification using covariate-adjusted interaction trees.

We consider the problem of identifying subgroups of participants in a clinical trial that have enhanced treatment effect. Recursive partitioning methods that recursively partition the covariate space based on some measure of between groups treatment effect difference are popular for such subgroup id...

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Bibliographic Details
Published in:Statistics in Medicine Vol. 38; no. 21; pp. 3974 - 3985
Main Authors: Steingrimsson, Jon Arni, Yang, Jiabei
Format: equations & formulas research tables/charts Journal Article
Published: Wiley-Blackwell 9/20/2019
Online Access:View this record in EBSCOhost