Suitability of intravascular imaging for assessment of cerebrovascular diseases.
Purpose: Arteriosclerosis of the vascular system is associated with many accompanying diseases. Especially cerebral arteriosclerosis is a main risk factor for ischemic strokes. We want to verify the practicability of intravascular imaging like intravascular ultrasound and optical coherence tomograph...
| Publicado en: | Neuroradiology Vol. 61; no. 9; pp. 1093 - 1102 |
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| Autores principales: | , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Sep2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137992594&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 137992594 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Sep2019 vid: 61 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 137992594 137992594 137992594 10.1007/s00234-019-02233-w 137992594 ppf: 1093 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Suitability of intravascular imaging for assessment of cerebrovascular diseases. aug: au: Weigand, S. Saalfeld, Sylvia Hoffmann, T. Eppler, E. Kalinski, T. Jachau, K. Skalej, M. affil: Department of Neuroradiology, University Hospital Magdeburg, Magdeburg, Germany sug: subj: Cerebrovascular Disorders Diagnosis Diagnostic Imaging Methods Human Tomography, Optical Coherence Ultrasonography Blood Vessels Pathology Cerebrovascular Disorders Pathology Quantitative Studies Comparative Studies Statistical Significance Histology ab: Purpose: Arteriosclerosis of the vascular system is associated with many accompanying diseases. Especially cerebral arteriosclerosis is a main risk factor for ischemic strokes. We want to verify the practicability of intravascular imaging like intravascular ultrasound and optical coherence tomography for the assessment of cerebral vessel walls and plaques. Methods: We examined 18 Circuli arteriosi willisii postmortem. The data contained 48 plaques from 48 different vessel parts. The samples underwent intravascular and histological imaging to conduct a quantitative assessment of vessel wall parameters (healthy vessel wall, thinnest vessel wall, plaque thickness and vessel diameter) as well as to qualitatively evaluate the healthy vessel wall, fibrotic plaques, calcifications and cholesterol deposits in diseased vessels. Results: The comparison showed statistically significant smaller measurements for thinnest vessel walls, normal vessel walls and vessel diameters in histology than in imaging. No statistically significant difference was reached for plaque diameters. Fibrotic plaques were characterized as hyper-intense with dorsal attenuation and calcifications as hypo-intense with dorsal attenuation in optical coherence tomography. In intravascular ultrasound, fibrotic plaques showed a homogeneous echogenicity without distal attenuation and calcifications were depicted as hyperechoic with dorsal sound shadows. Cholesterol deposits were hyper-intense in optical coherence tomography with strongly attenuated signals and in intravascular ultrasound; the deposits were hyper-intense with almost no attenuation. Conclusion: Both intravascular methods allow for plaque characterization and quantification of plaque diameter in cerebral vessel walls. When compared with histology, a statistically significant bias was obtained for the ex vivo measurements of the normal vessel wall diameters. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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