Impacts of inter-trial interval duration on a computational model of sign-tracking vs. goal-tracking behaviour.
In the context of Pavlovian conditioning, two types of behaviour may emerge within the population (Flagel et al. Nature, 469(7328): 53–57, 2011). Animals may choose to engage either with the conditioned stimulus (CS), a behaviour known as sign-tracking (ST) which is sensitive to dopamine inhibition...
| Publicado en: | Psychopharmacology Vol. 236; no. 8; pp. 2373 - 2389 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Aug2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138109928&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138109928 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00333158 EJD jtl: Psychopharmacology issn: 00333158 maglogo: N pubinfo: dt: Aug2019 vid: 236 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 138109928 10.1007/s00213-019-05323-y 138109928 ppf: 2373 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Impacts of inter-trial interval duration on a computational model of sign-tracking vs. goal-tracking behaviour. aug: au: Cinotti, François Marchand, Alain R. Roesch, Matthew R. Girard, Benoît Khamassi, Mehdi affil: CNRS, Institut des Systèmes Intelligents et de Robotique (ISIR), Équipe AMAC, Sorbonne Université, 4 Place Jussieu, 75252, Paris cedex 05, France sug: ab: In the context of Pavlovian conditioning, two types of behaviour may emerge within the population (Flagel et al. Nature, 469(7328): 53–57, 2011). Animals may choose to engage either with the conditioned stimulus (CS), a behaviour known as sign-tracking (ST) which is sensitive to dopamine inhibition for its acquisition, or with the food cup in which the reward or unconditioned stimulus (US) will eventually be delivered, a behaviour known as goal-tracking (GT) which is dependent on dopamine for its expression only. Previous work by Lesaint et al. (PLoS Comput Biol, 10(2), 2014) offered a computational explanation for these phenomena and led to the prediction that varying the duration of the inter-trial interval (ITI) would change the relative ST-GT proportion in the population as well as phasic dopamine responses. A recent study verified this prediction, but also found a rich variance of ST and GT behaviours within the trial which goes beyond the original computational model. In this paper, we provide a computational perspective on these novel results. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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