Computational modelling reveals contrasting effects on reinforcement learning and cognitive flexibility in stimulant use disorder and obsessive-compulsive disorder: remediating effects of dopaminergic D2/3 receptor agents.

Rationale: Disorders of compulsivity such as stimulant use disorder (SUD) and obsessive-compulsive disorder (OCD) are characterised by deficits in behavioural flexibility, some of which have been captured using probabilistic reversal learning (PRL) paradigms. Objectives: This study used computationa...

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Bibliographic Details

Published in:	Psychopharmacology Vol. 236; no. 8; pp. 2337 - 2359
Main Authors:	Kanen, Jonathan W., Ersche, Karen D., Fineberg, Naomi A., Robbins, Trevor W., Cardinal, Rudolf N.
Format:	Journal Article
Published:	Springer Nature Aug2019
Online Access:	View this record in EBSCOhost