Health utility and health-related quality of life of Japanese prostate cancer patients according to progression status measured using EQ-5D-5L and FACT-P.
Purpose: To obtain health utility data to allow for cost-effectiveness analysis in groups stratified by disease progression along with health-related quality of life (HRQoL) information in Japanese prostate cancer (PC) patients.Methods: In this cross-sectional observational study, EuroQol-5 Dimensio...
| Publicado en: | Quality of Life Research Vol. 28; no. 9; pp. 2383 - 2392 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Sep2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138126815&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138126815 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09629343 GPQ jtl: Quality of Life Research issn: 09629343 maglogo: N pubinfo: dt: Sep2019 vid: 28 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 138126815 138126815 144086091 NLM31025290 10.1007/s11136-019-02184-y NLM31025290 138126815 ppf: 2383 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Health utility and health-related quality of life of Japanese prostate cancer patients according to progression status measured using EQ-5D-5L and FACT-P. aug: au: Murasawa, Hideki Sugiyama, Takayuki Matsuoka, Yuki Okabe, Takashi Hino, Amiko Tanaka, Nobumichi Sugimoto, Mikio Oyama, Masafumi Fujimoto, Kiyohide Horie, Shigeo Noto, Shinichi Shimozuma, Kojiro affil: Department of Life Sciences, Ritsumeikan University, Kusatsu, Japan sug: subj: Quality of Life Psychosocial Factors Prostatic Neoplasms Psychosocial Factors Health Status Japan Aged Linear Regression Disease Progression Male Cross Sectional Studies Clinical Assessment Tools Scales Aged: 65+ years Male ab: Purpose: To obtain health utility data to allow for cost-effectiveness analysis in groups stratified by disease progression along with health-related quality of life (HRQoL) information in Japanese prostate cancer (PC) patients.Methods: In this cross-sectional observational study, EuroQol-5 Dimension- 5 Level (EQ-5D-5L), EuroQol Visual Analog Scale (EQ-VAS), and Functional Assessment of Cancer Therapy-Prostate (FACT-P) measures were used to examine utility, VAS scores, and disease-specific HRQoL, respectively. Scores obtained were statistically examined for the correlation among measures and domains. Parameter estimates of statistically significant factors were assessed using generalized linear models (GLM).Results: A total of 380 patients stratified by their disease progression status were analyzed. The numbers (%) of patients in groups stratified as having localized (L), localized progression (LP), distant metastatic (DM), and DM-castration-resistant PC (CRPC) were 275 (72.4), 40 (10.5), 27 (7.1), and 38 (10.0), respectively. EQ-5D-5L mean (standard deviation, SD) scores of L, LP, DM, and DM-CRPC in study participants were 0.87 (0.15), 0.86 (0.15), 0.85 (0.18), and 0.84 (0.17), respectively. The mean (SD) scores assessed by EQ-5D-5L, EQ-VAS, and FACT-P instruments were 0.86 (0.16), 74.6 (16.8), and 110.8 (19.6), respectively. Utility scores correlated well with FACT-P scores. Eastern Cooperative Oncology Group performance status had significant influences on all instruments' scores.Conclusions: We obtained health utility and HRQoL scores of Japanese PC patients stratified by disease progression in detail. Our results will be useful for establishing cost-effectiveness analyses in Japanese PC settings. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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