Pyoderma gangrenosum: a too often overlooked facultative paraneoplastic disease.

The frequency of concomitant malignant disease in PG patients has been estimated at 4.5-9% [[1]], and there have been increasing reports of PG in patients with an underlying solid malignancy [[2]] leading us to further characterize this association. Mortality was further analyzed using a univariate...

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Publicado en:Annals of Hematology Vol. 98; no. 9; pp. 2247 - 2249
Autores principales: Gupta, Angela S., Ortega-Loayza, Alex G.
Formato: review Journal Article
Publicado: Springer Nature Sep2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Pyoderma gangrenosum: a too often overlooked facultative paraneoplastic disease.
      aug:
        au:
          Gupta, Angela S.
          Ortega-Loayza, Alex G.
        affil: Virginia Commonwealth University School of Medicine, Richmond, VA, USA
      sug:
        subj:
          Pyoderma Gangrenosum Diagnosis
          Pyoderma Gangrenosum Pathology
          Paraneoplastic Syndromes Metabolism
          Paraneoplastic Syndromes Diagnosis
          Paraneoplastic Syndromes Pathology
          Pyoderma Gangrenosum Metabolism
          Diagnosis, Differential
          Male
          Female
          Male
          Female
      ab: The frequency of concomitant malignant disease in PG patients has been estimated at 4.5-9% [[1]], and there have been increasing reports of PG in patients with an underlying solid malignancy [[2]] leading us to further characterize this association. Mortality was further analyzed using a univariate logistic regression model which determined that patients with leukemia and PG have a higher likelihood of death compared with PG patients with non-leukemia hematologic malignancies ( I p i < 0.05, 95% CI = 1.01-3.34). <table frame="hsides" rules="groups"><thead><tr><th /><th>PG diagnosed before (%)</th><th>PG diagnosed after (%)</th><th>PG diagnosed at the same time (%)</th></tr></thead><tbody><tr><td>Hematologic malignancy</td><td>25</td><td>54</td><td>21</td></tr><tr><td>Solid malignancy</td><td>17</td><td>71</td><td>12</td></tr></tbody></table>.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Unknown
    language: English
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