Visual Evoked Potential in Nepalese Patients with Oculocutaneous Albinism: A Case Series.
Purpose: Visual evoked potential (VEP) is an important non-invasive tool used to augment the functions of the visual system. The present study aims to present the VEP recorded among Nepalese subjects with oculocutaneous albinism (OCA) and its correlation with clinical findings. Methods: In a cross-s...
| Publicado en: | Optometry & Visual Performance Vol. 7; no. 3; pp. 186 - 194 |
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| Autores principales: | , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Optometric Extension Program
Jul2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138164750&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138164750 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23253479 HOOW jtl: Optometry & Visual Performance issn: 23253479 maglogo: N pubinfo: dt: Jul2019 vid: 7 iid: 3 pid: 46881 pub: Optometric Extension Program place: Lutherville Timonium, Maryland artinfo: ui: 138164750 138164750 138164750 138164750 ppf: 186 ppct: 8 formats: tig: atl: Visual Evoked Potential in Nepalese Patients with Oculocutaneous Albinism: A Case Series. aug: au: Shrestha, Gauri Shankar Dahal, Hira Nath Thapa, Madhu affil: B.P. Koirala Lions Center for Ophthalmic Studies, Tribhuvan University • Maharajgunj, Kathmandu sug: subj: Evoked Potentials, Visual Albinism Physiopathology Human Nepal Cross Sectional Studies Sensitivity and Specificity Nystagmus, Pathologic Strabismus Transillumination Visual Acuity Data Analysis Software Descriptive Statistics Paired T-Tests Unpaired T-Tests Multiple Linear Regression Male Female Adolescence Adult Mydriatics Color Perception Depth Perception Adolescent: 13-18 years Adult: 19-44 years Male Female ab: Purpose: Visual evoked potential (VEP) is an important non-invasive tool used to augment the functions of the visual system. The present study aims to present the VEP recorded among Nepalese subjects with oculocutaneous albinism (OCA) and its correlation with clinical findings. Methods: In a cross-sectional study, 10 consecutive subjects with OCA and 10 age-/sexmatched normal subjects were selected for a pattern reversal VEP test using the Retiscan Roland electrophysiological diagnostic system. Apart from VEP, OCA subjects' anterior and posterior segments were examined to record clinical findings. Contrast sensitivity with the Pelli-Robson chart, colour vision with the Farnsworth D-15 test, stereopsis with the Titmus vectographic plates, and cycloplegic refraction were also performed. Statistical analysis included paired t-test, independent sample t-test, and multiple linear regression analysis. Results: Clinical OCA features seen in study patients included horizontal pendular nystagmus in seven subjects, strabismus in four subjects, iris transillumination in seven subjects, disc hypoplasia in two subjects, and macular hypoplasia in four subjects. The mean VEP amplitudes were found to be significantly lower in subjects with albinism than in normal subjects in both right and left eyes for all frequencies. Strabismus (p<0.001 for N75-P100, low frequency; p<0.001 for N75-P100, high frequency; and p=0.021 for P100-N135, high frequency) and nystagmus (p=0.004 for P100-N135, high frequency and p=0.044 for P100-N135, low frequency) were significantly correlated with the amplitudes of pattern VEP. Mostly, P100-N135 high frequency was associated with clinical findings. Conclusion: The amplitude of pattern reversal VEP is significantly reduced in albinism, which is correlated with strabismus and nystagmus. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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