Automated Detection of Alzheimer's Disease Using Brain MRI Images– A Study with Various Feature Extraction Techniques.

The aim of this work is to develop a Computer-Aided-Brain-Diagnosis (CABD) system that can determine if a brain scan shows signs of Alzheimer's disease. The method utilizes Magnetic Resonance Imaging (MRI) for classification with several feature extraction techniques. MRI is a non-invasive procedure...

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Publicado en:Journal of Medical Systems Vol. 43; no. 9
Autores principales: Acharya, U. Rajendra, Fernandes, Steven Lawrence, WeiKoh, Joel En, Ciaccio, Edward J., Fabell, Mohd Kamil Mohd, Tanik, U. John, Rajinikanth, V., Yeong, Chai Hong
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Sep2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2019
      vid: 43
      iid: 9
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-019-1428-9
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        atl: Automated Detection of Alzheimer's Disease Using Brain MRI Images– A Study with Various Feature Extraction Techniques.
      aug:
        au:
          Acharya, U. Rajendra
          Fernandes, Steven Lawrence
          WeiKoh, Joel En
          Ciaccio, Edward J.
          Fabell, Mohd Kamil Mohd
          Tanik, U. John
          Rajinikanth, V.
          Yeong, Chai Hong
        affil: Department of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore, Singapore
      sug:
        subj:
          Alzheimer's Disease Diagnosis
          Brain Pathology
          Magnetic Resonance Imaging Methods
          Automation, Laboratory
          Human
          Image Processing, Computer Assisted
          T-Tests
          Comparative Studies
          Sensitivity and Specificity
          Equipment Reliability
          Experimental Studies
          Machine Learning
          Technology, Medical
          Deep Learning
      ab: The aim of this work is to develop a Computer-Aided-Brain-Diagnosis (CABD) system that can determine if a brain scan shows signs of Alzheimer's disease. The method utilizes Magnetic Resonance Imaging (MRI) for classification with several feature extraction techniques. MRI is a non-invasive procedure, widely adopted in hospitals to examine cognitive abnormalities. Images are acquired using the T2 imaging sequence. The paradigm consists of a series of quantitative techniques: filtering, feature extraction, Student's t-test based feature selection, and k-Nearest Neighbor (KNN) based classification. Additionally, a comparative analysis is done by implementing other feature extraction procedures that are described in the literature. Our findings suggest that the Shearlet Transform (ST) feature extraction technique offers improved results for Alzheimer's diagnosis as compared to alternative methods. The proposed CABD tool with the ST + KNN technique provided accuracy of 94.54%, precision of 88.33%, sensitivity of 96.30% and specificity of 93.64%. Furthermore, this tool also offered an accuracy, precision, sensitivity and specificity of 98.48%, 100%, 96.97% and 100%, respectively, with the benchmark MRI database.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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