An iterative damped least-squares algorithm for simultaneously monitoring the development of hemorrhagic and secondary ischemic lesions in brain injuries.

Electrical impedance tomography (EIT) is a non-invasive and real-time imaging method that has the potential to be used for monitoring intracerebral hemorrhage (ICH). Recent studies have proposed that ischemia secondary to ICH occurs simultaneously in the brain. Real-time monitoring of the developmen...

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Publicado en:Medical & Biological Engineering & Computing Vol. 57; no. 9; pp. 1917 - 1932
Autores principales: Liu, Xuechao, Li, Haoting, Ma, Hang, Xu, Canhua, Yang, Bin, Dai, Meng, Dong, Xiuzhen, Fu, Feng
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Sep2019
Acceso en línea:Ver este registro en EBSCOhost
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      place: New York, New York
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        atl: An iterative damped least-squares algorithm for simultaneously monitoring the development of hemorrhagic and secondary ischemic lesions in brain injuries.
      aug:
        au:
          Liu, Xuechao
          Li, Haoting
          Ma, Hang
          Xu, Canhua
          Yang, Bin
          Dai, Meng
          Dong, Xiuzhen
          Fu, Feng
        affil: Department of Biomedical Engineering, Air Force Military Medical University, Xi'an, China
      sug:
        subj:
          Cerebral Ischemia Pathology
          Algorithms
          Brain Injuries Pathology
          Intracranial Hemorrhage Pathology
          Monitoring, Physiologic Methods
          Phantoms, Imaging
          Brain Injuries Complications
          Tomography, X-Ray Computed
          Computer Simulation
          Image Processing, Computer Assisted Methods
          Electric Impedance
          Regression
          Funding Source
          Human
      ab: Electrical impedance tomography (EIT) is a non-invasive and real-time imaging method that has the potential to be used for monitoring intracerebral hemorrhage (ICH). Recent studies have proposed that ischemia secondary to ICH occurs simultaneously in the brain. Real-time monitoring of the development of hemorrhage and risk of secondary ischemia is crucial for clinical intervention. However, few studies have explored the performance of EIT monitoring in cases where hemorrhage and secondary ischemia exist. When these lesions get close to each other, or their conductivity and volume changes differ greatly, it becomes challenging for dynamic EIT algorithms to simultaneously reconstruct subtle injuries. To address this, an iterative damped least-squares (IDLS) algorithm is proposed in this study. The quality of the IDLS algorithm was assessed using blur radius and temporal response during computer simulation and a phantom 3D head-shaped model where bidirectional disturbance targets were simulated. The results showed that the IDLS algorithm enhanced contrast and concurrently reconstructed bidirectional disturbance targets in images. Moreover, it showed superior performance in decreasing the blur radius and was time cost-effective. With further improvement, the IDLS algorithm has the potential to be used for monitoring the development of hemorrhage and risk of ischemia secondary to ICH. Graphical abstract (a) and (b) are simulation images of bidirectional disturbance targets with different change ratios of volume (Vr) and conductivity (σr) based on the damped least-squares (DLS) algorithm and iterative damped least-squared (IDLS) algorithm, respectively. (c) shows the performance metrics of blur radius and temporal response with different volume ratio (corresponding to Vr). (d) shows the performance metrics of blur radius and temporal response with different conductivity change percentage (corresponding to σr).
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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