Stimulant medication in 47,XYY syndrome: a report of two cases.

In two males, 11 and 12 years of age, referred for attention-deficit-hyperactivity disorder (ADHD), 47,XYY syndrome was diagnosed. A team that included a neuropsychologist, a physiotherapist, and a physician examined them. Stature (patients were above 97.5% height for age), muscle consistency, and t...

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Publicado en:Developmental Medicine & Child Neurology Vol. 47; no. 8; pp. 559 - 563
Autores principales: Ruud, Anne, Arnesen, Peter, Stray, Liv Larsen, Vildalen, Stéphane, Vesterhus, Per
Formato: case study Journal Article
Publicado: Wiley-Blackwell Aug2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2005
      vid: 47
      iid: 8
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Stimulant medication in 47,XYY syndrome: a report of two cases.
      aug:
        au:
          Ruud, Anne
          Arnesen, Peter
          Stray, Liv Larsen
          Vildalen, Stéphane
          Vesterhus, Per
        affil: Sorlandet Resource Centre, Kristiansand, Norway
      sug:
        subj:
          Central Nervous System Stimulants Therapeutic Use
          Methylphenidate Therapeutic Use
          Attention Deficit Hyperactivity Disorder
          Sex Chromosome Aberrations
          Attention Deficit Hyperactivity Disorder Drug Therapy
          Dose-Response Relationship, Drug
          Cognition Disorders Etiology
          Severity of Illness Indices
          Male
          Cognition Disorders Diagnosis
          Neuropsychological Tests
          Attention Deficit Hyperactivity Disorder Complications
          Child
          Scales
          Social Readjustment Rating Scale
          Child: 6-12 years
          Male
      ab: In two males, 11 and 12 years of age, referred for attention-deficit-hyperactivity disorder (ADHD), 47,XYY syndrome was diagnosed. A team that included a neuropsychologist, a physiotherapist, and a physician examined them. Stature (patients were above 97.5% height for age), muscle consistency, and tremor indicated chromosome analysis. Psychological tests results did not fully fit the ADHD diagnosis. On the basis of our clinical observation we felt that stimulant medication was indicated. Administration of methylphenidate led to improved motor and cognitive functions as well as social adaptation in both patients. We suggest that this treatment might well be considered in clinically similar patients with XYY sex chromosomes; we further suggest that learning problems in such individuals may be related to ADHD.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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