Cover Image
QR Code

Use of the World Wide Web in research: randomization in a multicenter clinical trial of treatment for twin-twin transfusion syndrome.

Objective: To describe the process involved in using the World Wide Web to coordinate a randomized, multicenter international trial of treatment for twin-twin transfusion syndrome.Method: A Web site was designed by members of the research team, a Web consultant, and a senior computer programmer. The...

Full description

Published in:Obstetrics & Gynecology Vol. 96; no. 4; pp. 636 - 640
Main Authors: Dorman, K, Saade, G R, Smith, H, Moise, K J Jr
Format: clinical trial research randomized controlled trial Journal Article
Published: Lippincott Williams & Wilkins 2000 Oct
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138223029&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 138223029
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        00297844
        22Z
      jtl: Obstetrics & Gynecology
      issn: 00297844
      maglogo: N
    pubinfo:
      dt: 2000 Oct
      vid: 96
      iid: 4
      pid: 433
      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
    artinfo:
      ui:
        138223029
        138223029
        NLM11041770
        138223029
        NLM11041770
        138223029
      ppf: 636
      ppct: 4
      formats:
      tig:
        atl: Use of the World Wide Web in research: randomization in a multicenter clinical trial of treatment for twin-twin transfusion syndrome.
      aug:
        au:
          Dorman, K
          Saade, G R
          Smith, H
          Moise, K J Jr
        affil: Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill 27599, USA
      sug:
        subj:
          Multicenter Studies
          Internet
          Clinical Trials
          Fetofetal Transfusion Therapy
          Female
          Communication
          Human
          International Relations
          Pregnancy
          Validation Studies
          Comparative Studies
          Evaluation Research
          Randomized Controlled Trials
          Scales
          Female
      ab: Objective: To describe the process involved in using the World Wide Web to coordinate a randomized, multicenter international trial of treatment for twin-twin transfusion syndrome.Method: A Web site was designed by members of the research team, a Web consultant, and a senior computer programmer. The original intent was to provide patient randomization only, but the Web site later was designed so that centers could download a data collection form. Data could be entered directly into the Web site and subsequently imported into a database at the coordinating center.Experience: The Web site has been active for 3 years, with 13 participating centers and 31 patients enrolled.Comment: Use of the World Wide Web to coordinate an international, multicenter trial is an efficient method. Although there are many benefits, the most obvious is the capability to initiate and conduct a large international trial at minimal cost.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N