Epidemiology of β-Lactamase-Producing Staphylococci and Gram Negative Bacteria as Cause of Clinical Bovine Mastitis in Tunisia.

The aim of this study was to determine the species distribution of Staphylococcus, Gram negative bacteria (GNB) and the occurrence of Methicillin Resistant Staphylococci (MRS) and Extended-Spectrum β-lactamase- (ESBL-) producing GNB. Bacterial culture of 300 clinical mastitis milk samples from 30 di...

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Publicado en:BioMed Research International pp. 1 - 10
Autores principales: Klibi, Amira, Jouini, Ahlem, Boubaker El Andolsi, Ramzi, Kmiha, Souhir, Ben Hamda, Cherif, Ghedira, Kais, Hamrouni, Safa, Ghram, Abdeljalil, Maaroufi, Abderrazek
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 8/27/2019
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
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    pubinfo:
      dt: 8/27/2019
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        138290877
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        10.1155/2019/2165316
        138290877
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        atl: Epidemiology of β-Lactamase-Producing Staphylococci and Gram Negative Bacteria as Cause of Clinical Bovine Mastitis in Tunisia.
      aug:
        au:
          Klibi, Amira
          Jouini, Ahlem
          Boubaker El Andolsi, Ramzi
          Kmiha, Souhir
          Ben Hamda, Cherif
          Ghedira, Kais
          Hamrouni, Safa
          Ghram, Abdeljalil
          Maaroufi, Abderrazek
        affil: Laboratory of Epidemiology and Veterinary Microbiology, Group of Bacteriology and Biotechnology Development, Institut Pasteur de Tunis, BP 74, 13 Place Pasteur, Belvédère, 1002 Tunis, Tunisia
      sug:
        subj:
          Staphylococcus Transmission
          Gram-Negative Bacteria Transmission
          Methicillin-Resistant Staphylococcus Aureus Transmission
          Zoonoses Microbiology
          Zoonoses Epidemiology
          Animal Studies
          Cattle
          Tunisia
          Milk Analysis
          Staphylococcus Analysis
          Gram-Negative Bacteria Analysis
          Methicillin-Resistant Staphylococcus Aureus Analysis
          Virulence
          Agriculture
          Seasons
          Escherichia Coli Analysis
          Peptide Hydrolases
          Klebsiella Analysis
          Staphylococcus Aureus Analysis
          Genes
          Cefotaxime
          Microbial Culture and Sensitivity Tests
          Amidohydrolases
      ab: The aim of this study was to determine the species distribution of Staphylococcus, Gram negative bacteria (GNB) and the occurrence of Methicillin Resistant Staphylococci (MRS) and Extended-Spectrum β-lactamase- (ESBL-) producing GNB. Bacterial culture of 300 clinical mastitis milk samples from 30 different farms across different regions of Tunisia during four seasons was realized. The obtained results showed the presence of high frequency of the tested samples with a positive growth for bacteria (64%). In addition a high recovery rate of Staphylococci and/or GNB in these clinical mastitis milk samples (87%) was detected. In addition, a high percentage of GNB (68.2%) compared to Staphylococcus species (32%) was noted. Moreover, a significant variation of the number of these bacteria according to the farm location, the seasons, and cows age was detected. The highest percentage was observed in the North of Tunisia during the winter and the spring seasons in adult cows with a dominance of GNB growth. Coagulase negative Staphylococci (CNS) (n=11) and GNB (n=16) species were identified. Escherichia coli (E. coli) was the most frequently found bacterium followed by Klebsiella pneumoniae. The dominant Staphylococcus isolates was S. xylosus followed by S. aureus the major pathogen isolated. Methicillin resistance was confirmed by the presence of the mecA gene in 3 S. aureus and 14 CNS isolates; all of these isolates were lacking the mecC gene. Various species of GNB, resistant to cefotaxime, were detected (n=15). ESBLs were detected on selective medium in 10 E. coli and 4 K. pneumoniae. All ESBL producers strains carry the blaCTX-M. The presence of different resistant mastitis pathogens in dairy farms may complicate therapeutic options and contaminated animals could become zoonotic agent reservoir for human.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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