Adherence and quality of life in women with breast cancer being treated with oral hormone therapy.

Purpose: To evaluate adherence to oral hormone therapy (HT) and which factors impact in incomplete adherence and quality of life.Methods: This was a cross-sectional study.Setting: Women's Hospital Prof. Dr. José Aristodemo Pinotti.Participants: women with breast cancer under treatment with oral HT.M...

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Publicado en:Supportive Care in Cancer Vol. 27; no. 10; pp. 3799 - 3805
Autores principales: Stahlschmidt, Rebeca, Ferracini, Amanda Canato, de Souza, Cinthia Madeira, de Medeiros, Luana Moreira, Juliato, Cassia Raquel Teatin, Mazzola, Priscila Gava
Formato: research tables/charts Journal Article
Publicado: Springer Nature Oct2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2019
      vid: 27
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      pub: Springer Nature
      place: New York, New York
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        atl: Adherence and quality of life in women with breast cancer being treated with oral hormone therapy.
      aug:
        au:
          Stahlschmidt, Rebeca
          Ferracini, Amanda Canato
          de Souza, Cinthia Madeira
          de Medeiros, Luana Moreira
          Juliato, Cassia Raquel Teatin
          Mazzola, Priscila Gava
        affil: Faculty of Medical Sciences, University of Campinas (Unicamp), Tessália Vieira de Camargo Street, 126, Cidade Universitária "Zeferino Vaz", 13083-887, Campinas, SP, Brazil
      sug:
        subj:
          Antineoplastic Agents, Hormonal Therapeutic Use
          Aromatase Inhibitors Therapeutic Use
          Tamoxifen Therapeutic Use
          Breast Neoplasms Drug Therapy
          Quality of Life Psychosocial Factors
          Middle Age
          Cross Sectional Studies
          Female
          Breast Neoplasms Psychosocial Factors
          Ferrans and Powers Quality of Life Index
          Impact of Events Scale
          Human
          Funding Source
          Middle Aged: 45-64 years
          Female
      ab: Purpose: To evaluate adherence to oral hormone therapy (HT) and which factors impact in incomplete adherence and quality of life.Methods: This was a cross-sectional study.Setting: Women's Hospital Prof. Dr. José Aristodemo Pinotti.Participants: women with breast cancer under treatment with oral HT.Main Outcome Measures: interview and performed an adherence questionnaire (Morisky-Green) and two questionnaires of quality of life (EORTC-QLQ30/BR23). The interviews were done once in a 5-month period.Results: Fifty-eight women were interviewed: 42 under treatment with tamoxifen (TX) and 16 under treatment with aromatase inhibitor (AI). Twenty-six women (44%) showed high adherence to the treatment, 31 (54%) medium adherence, and 1 (2%) low adherence. Statistical analysis showed a relation between incomplete adherence and systemic therapy side effects as well as higher stages of disease, with no difference between the two drugs. When treatments were compared, this study showed treatment with AI presented less breast symptoms and better role functioning. Quality of life score was high, compared to the reference value.Conclusions: A low percentage of women with breast cancer were highly adherent to HT treatment. Low/medium adherence was associated with higher stages of disease and systemic side effects. Quality of life had high scores, with better role function and less breast symptoms in women being treated with an AI.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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