A group sequential test for ABR detection.
Objective: To detect the auditory brainstem response (ABR) automatically using an innovative sequentially applied Hotelling's T 2 test, with the overall goal of optimising test time whilst controlling the false-positive rate (FPR). Design: The stage-wise critical decision boundaries for accepting or...
| Publicado en: | International Journal of Audiology Vol. 58; no. 10; pp. 618 - 628 |
|---|---|
| Autores principales: | , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Oct2019
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138433724&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138433724 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14992027 JW2 jtl: International Journal of Audiology issn: 14992027 maglogo: Y pubinfo: dt: Oct2019 vid: 58 iid: 10 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 138433724 138433724 138433724 10.1080/14992027.2019.1625486 138433724 ppf: 618 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A group sequential test for ABR detection. aug: au: Chesnaye, M. A. Bell, S. L. Harte, J. M. Simpson, D. M. affil: Faculty of Engineering and the Environment, Institute of Sound and Vibration Research, University of Southampton, UK sug: subj: Hearing Disorders Diagnosis Evoked Potentials, Auditory, Brainstem Evaluation Hearing Tests Methods Sensitivity and Specificity Evaluation Human Male Female Electroencephalography Time Factors Auditory Threshold False Positive Results Hearing Tests Equipment and Supplies Auditory Steady-State Response Reflex, Acoustic Acoustic Stimulation Confidence Intervals Funding Source Male Female ab: Objective: To detect the auditory brainstem response (ABR) automatically using an innovative sequentially applied Hotelling's T 2 test, with the overall goal of optimising test time whilst controlling the false-positive rate (FPR). Design: The stage-wise critical decision boundaries for accepting or rejecting the null hypothesis were found using a new approach called the Convolutional Group Sequential Test (CGST). Specificity, sensitivity, and test time were evaluated using simulations and subject recorded data. Study sample: Data consists of click-evoked ABR threshold series from 12 normal hearing adults, and recordings of EEG background activity from 17 normal hearing adults. Results: Reductions in mean test time of up to 40–45% were observed for the sequential test, relative to a conventional "single shot" test where the statistical test is applied to the data just once. To obtain these results, it will occasionally be necessary to run the test to a higher number of stimuli, i.e. the maximum test time needs to be increased. Conclusions: The CGST can be used to control the specificity of a sequentially applied ABR detection method. Doing so can reduce test time, relative to the "single shot" test, when considered across a cohort of test subjects. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|