Evaluation of a new algorithm for tracking activation during atrial fibrillation using multipolar catheters in humans.

Background: Conventional mapping techniques during atrial fibrillation (AF) are difficult to apply because of cycle length irregularity. Mapping studies are usually restricted to short durations of AF in limited regions because of the laborious manual annotation of local activation time (LAT). The p...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 30; no. 9; pp. 1464 - 1475
Autores principales: Mann, Ian, Coyle, Clare, Qureshi, Norman, Nagy, Szabolcs Z, Koa‐Wing, Michael, Lim, Phang Boon, Francis, Darrel P, Whinnett, Zachary, Peters, Nicholas S, Kanagaratnam, Prapa, Linton, Nick W.F.
Formato: diagnostic images equations & formulas pictorial research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell Sep2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jce.14033
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        atl: Evaluation of a new algorithm for tracking activation during atrial fibrillation using multipolar catheters in humans.
      aug:
        au:
          Mann, Ian
          Coyle, Clare
          Qureshi, Norman
          Nagy, Szabolcs Z
          Koa‐Wing, Michael
          Lim, Phang Boon
          Francis, Darrel P
          Whinnett, Zachary
          Peters, Nicholas S
          Kanagaratnam, Prapa
          Linton, Nick W.F.
        affil: Imperial College Healthcare NHS Trust, London UK
      sug:
        subj:
          Body Surface Potential Mapping Methods
          Algorithms Evaluation
          Atrial Fibrillation Diagnosis
          Heart Atrium, Left Surgery
          Catheters
          Sensitivity and Specificity
          Human
          Electrodes, Implanted
          Heart Function Tests Methods
          Research Ethics
      ab: Background: Conventional mapping techniques during atrial fibrillation (AF) are difficult to apply because of cycle length irregularity. Mapping studies are usually restricted to short durations of AF in limited regions because of the laborious manual annotation of local activation time (LAT). The purpose of this study was to test an automated algorithm to map activation during AF, with comparable accuracy to manual annotation. Methods: Left atrial (LA) mapping was performed using a 20‐pole double loop catheter (AFocusII) in 30‐second data segments from 16 patients. The new algorithm (RETRO‐Mapping) was designed to detect wavefront propagation between electrodes, and display activating wavefronts on a two‐dimensional representation of the catheter. Activation patterns were validated against their bipolar electrograms and with isochronal maps. The mapping protocol was approved by the research ethics committee (13/LO1169 and 14/LO1367). Results: During AF, uniform wavefront activation direction (mean ± SD, degrees) from manually constructed isochronal maps was comparable to RETRO‐Propagation Map (RETRO‐PM) and RETRO‐Automated Direction (RETRO‐AD): 1 ± 6.9 for RETRO‐PM; and 2 ± 6.6 for RETRO‐AD. There was no significant difference in activation direction assigned to 1373 uniform wavefronts during AF when comparing RETRO‐PM with RETRO‐AD (Bland‐Altman mean difference: −0.1 degrees; limits of agreement: −8.0 to 8.3; 95% CI −0.4 to 0.2; (r = 0.01) R2 = < 0.005; P = .77). Conclusion: We have developed and validated a new technique to map activation during AF. This technique shows comparable accuracy to that of conventional isochronal mapping with careful manual adjustment of LAT.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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