Joint representation of connectome-scale structural and functional profiles for identification of consistent cortical landmarks in macaque brain.

Discovery and representation of common structural and functional cortical architectures has been a significant yet challenging problem for years. Due to the remarkable variability of structural and functional cortical architectures in human brain, it is challenging to jointly represent a common cort...

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Publicado en:Brain Imaging & Behavior Vol. 13; no. 5; pp. 1427 - 1444
Autores principales: Zhang, Shu, Jiang, Xi, Zhang, Wei, Zhang, Tuo, Chen, Hanbo, Zhao, Yu, Lv, Jinglei, Guo, Lei, Howell, Brittany R., Sanchez, Mar M., Hu, Xiaoping, Liu, Tianming
Formato: Journal Article
Publicado: Springer Nature Oct2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Joint representation of connectome-scale structural and functional profiles for identification of consistent cortical landmarks in macaque brain.
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          Zhang, Shu
          Jiang, Xi
          Zhang, Wei
          Zhang, Tuo
          Chen, Hanbo
          Zhao, Yu
          Lv, Jinglei
          Guo, Lei
          Howell, Brittany R.
          Sanchez, Mar M.
          Hu, Xiaoping
          Liu, Tianming
        affil: Cortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, Boyd GSRC 420, 30602, Athens, GA, USA
      sug:
        subj:
          Brain Physiology
          Primates
          Brain Mapping Methods
          Brain
          Animals
          Magnetic Resonance Imaging
          Clinical Assessment Tools
      ab: Discovery and representation of common structural and functional cortical architectures has been a significant yet challenging problem for years. Due to the remarkable variability of structural and functional cortical architectures in human brain, it is challenging to jointly represent a common cortical architecture which can comprehensively encode both structure and function characteristics. In order to better understand this challenge and considering that macaque monkey brain has much less variability in structure and function compared with human brain, in this paper, we propose a novel computational framework to apply our DICCCOL (Dense Individualized and Common Connectivity-based Cortical Landmarks) and HAFNI (Holistic Atlases of Functional Networks and Interactions) frameworks on macaque brains, in order to jointly represent structural and functional connectome-scale profiles for identification of a set of consistent and common cortical landmarks across different macaque brains based on multimodal DTI and resting state fMRI (rsfMRI) data. Experimental results demonstrate that 100 consistent and common cortical landmarks are successfully identified via the proposed framework, each of which has reasonably accurate anatomical, structural fiber connection pattern, and functional correspondences across different macaque brains. This set of 100 landmarks offer novel insights into the structural and functional cortical architectures in macaque brains.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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