A Privacy Preserving Approach to Feasibility Analyses on Distributed Data Sources in Biomedical Research.
Funding agencies and field experts promote reuse of scientific data and biomaterial beyond the scope of the original project. The availability of research data, however, is limited by the interest of original authors as well as the privacy rights of the study participants, especially in the biomedic...
| Publicado en: | Studies in Health Technology & Informatics Vol. 267; pp. 254 - 262 |
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| Autores principales: | , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138512482&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138512482 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09269630 U1V jtl: Studies in Health Technology & Informatics issn: 09269630 maglogo: N pubinfo: dt: 2019 vid: 267 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 138512482 138512482 138512482 10.3233/SHTI190835 138512482 ppf: 254 ppct: 8 formats: tig: atl: A Privacy Preserving Approach to Feasibility Analyses on Distributed Data Sources in Biomedical Research. aug: au: SCHEEL, Heiko DATHE, Henning FRANKE, Thomas SCHARFE, Tabea ROTTMANN, Thorsten affil: Department of Medical Informatics, University Medical Center Göttingen sug: subj: Research, Medical Data Management Data Security Software Design Human Information Retrieval Data Mining Data Analytics Graphical User Interface Consent Funding Source ab: Funding agencies and field experts promote reuse of scientific data and biomaterial beyond the scope of the original project. The availability of research data, however, is limited by the interest of original authors as well as the privacy rights of the study participants, especially in the biomedical sciences. On the other hand, for an available data set to be a useful contribution to the scientific community, it has to be findable and accessible with reasonable effort. Therefore, using the R Shiny library, we designed and implemented a software for data discovery and feasibility analyses with compliance to regulatory and contractual regulations. Due to its genericity, it was successfully tested with heterogeneous data sets and ultimately applied to the data and biomaterial of the German Center for Cardiovascular Research (DZHK). The resulting tool - named the Feasibility Explorer - is publicly available and can be used by researchers to get an overview of data and biomaterial available in the DZHK and to select collectives in the process of submitting a usage application. To implement the rights of participants and original authors, data is integrated by querying the informed consent and not persistently stored. All calculations on the data are performed server-sided and only aggregated information is send to a client, whereas the extent of information was strictly limited to a necessary minimum that allows an applicant to assess whether an application is worthwhile. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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