Memory improvement in African Americans with amnestic mild cognitive impairment.
Objective: Amnestic mild cognitive impairment (aMCI) has an uncertain course. Valid methods to evaluate memory change will best identify predictors of course. This issue is especially relevant to older persons in minority groups, who may have encountered life course factors that adversely affect cog...
| Publicado en: | International Journal of Geriatric Psychiatry Vol. 34; no. 10; pp. 1447 - 1455 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138570509&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138570509 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08856230 BWG jtl: International Journal of Geriatric Psychiatry issn: 08856230 maglogo: Y pubinfo: dt: Oct2019 vid: 34 iid: 10 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 138570509 138570509 NLM31087388 138570509 10.1002/gps.5141 NLM31087388 138570509 ppf: 1447 ppct: 8 formats: tig: atl: Memory improvement in African Americans with amnestic mild cognitive impairment. aug: au: Rovner, Barry W. Casten, Robin J. Leiby, Benjamin affil: Departments of Neurology, Psychiatry, and Ophthalmology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia Pennsylvania sug: subj: African Americans Statistics and Numerical Data Amnesia Diagnosis Memory Neuropsychological Tests Cognition Male Aged, 80 and Over Aged Female Middle Age Risk Factors Funding Source Human Aged, 80 & over Aged: 65+ years Middle Aged: 45-64 years Male Female ab: Objective: Amnestic mild cognitive impairment (aMCI) has an uncertain course. Valid methods to evaluate memory change will best identify predictors of course. This issue is especially relevant to older persons in minority groups, who may have encountered life course factors that adversely affect cognition.Methods/design: Growth curve mixture models were used to identify trajectories of memory test scores obtained every 6 months over 2 years in 221 African Americans with aMCI.Results: Participants sorted into two classes, with clinically and statistically significant differences in memory scores over time. Class 1 (n = 28 [14.7%]) had sustained improved scores. Class 2 (n = 162 [85.3%]) scores remained low, fluctuated, or declined. Class 1 had better baseline cognition and daily function than class 2.Conclusions: The observed rate of improved memory is lower than reported reversion rates from aMCI to normal cognition. Evaluating trajectories of memory test scores rather than changes in categorical diagnoses of aMCI, which may depend on recalling (or not recalling) one or two words, may yield a more valid indicator of cognitive change. These approaches require further study in minority groups. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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