The effectiveness of noninvasive ventilation in myasthenia gravis subjects with respiratory failure in reducing the need of endotracheal intubation and increase extubation outcomes.

Background: Myasthenia gravis is characterized by muscle weakness and fatigability. The affected muscle are ocular muscle, oropharyngeal muscle, facial muscle, and respiratory muscle. This leads to respiratory failure in myasthenia gravis patients with myasthenic crisis. Noninvasive ventilation has...

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Publicado en:Critical Care & Shock Vol. 22; no. 4; pp. 189 - 197
Autores principales: Farhana, Nadya, Amin, Zulkifli
Formato: research systematic review tables/charts Journal Article
Publicado: Critical Care & Shock Journal 2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Critical Care & Shock Journal
      place: Houston, Texas
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        atl: The effectiveness of noninvasive ventilation in myasthenia gravis subjects with respiratory failure in reducing the need of endotracheal intubation and increase extubation outcomes.
      aug:
        au:
          Farhana, Nadya
          Amin, Zulkifli
        affil: Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
      sug:
        subj:
          Respiration, Artificial Evaluation
          Respiratory Failure Therapy
          Noninvasive Procedures
          Myasthenia Gravis
          Intubation, Intratracheal
          Extubation
          Outcomes (Health Care)
          Human
          Systematic Review
          PubMed
          Cochrane Library
          Length of Stay
          Descriptive Statistics
      ab: Background: Myasthenia gravis is characterized by muscle weakness and fatigability. The affected muscle are ocular muscle, oropharyngeal muscle, facial muscle, and respiratory muscle. This leads to respiratory failure in myasthenia gravis patients with myasthenic crisis. Noninvasive ventilation has been used to treat patients with hypercapnia respiratory failure and associated with reduction of the need of endotracheal intubation, reduction of complication rate, reduction of hospital stays, and reduction of mortality. In myasthenia gravis patients with respiratory failure, there is no evidence that noninvasive ventilation would reduce those factors. Thus, we studied the effectiveness of non-invasive ventilation in myasthenia gravis patients with respiratory failure in reducing the need of endotracheal intubation and increase extubation outcomes. Methods: Literature review on PubMed, Elton B. Stephens Co. (EBSCO), Cochrane, and ScienceDirect yield two relevant articles. Results: Two studies showed that noninvasive ventilation in subject with myasthenia gravis with respiratory failure had better effect. Conclusion: It is effective to use noninvasive ventilation in subject with myasthenia gravis during their respiratory failure in myasthenic crisis.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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