Characterization of myocardial tissue in patients undergoing maintenance hemodialysis by quantitative echocardiography.
The uremic state affects myocardial structure, bringing about, among other things, interstitial calcium deposition. Abnormalities of myocardial structure can be assessed quantitatively and noninvasively during life by the analysis of the gray-level distribution of conventional two-dimensional echoca...
| Publicado en: | Journal of the American Society of Echocardiography Vol. 9; no. 4; pp. 480 - 488 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
1996 Jul-Aug
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138609245&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138609245 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08947317 4CO jtl: Journal of the American Society of Echocardiography issn: 08947317 maglogo: N pubinfo: dt: 1996 Jul-Aug vid: 9 iid: 4 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 138609245 138609245 NLM8827631 138609245 NLM8827631 138609245 ppf: 480 ppct: 8 formats: tig: atl: Characterization of myocardial tissue in patients undergoing maintenance hemodialysis by quantitative echocardiography. aug: au: Morales, M A Ferdeghini, E M Pizzarelli, F Piacenti, M Dattolo, P Pelosi, G Distante, A Maggiore, Q affil: National Research Council Clinical Physiology Institute, Santa Maria Annunziata Hospital, Pisa, Italy sug: subj: Echocardiography Methods Hemodialysis Aged Middle Age Phosphates Metabolism Hypertension Female Human Heart Septum Hypertrophy, Left Ventricular Uremia Reproducibility of Results Calcium Metabolism Aged, 80 and Over Male Adult Validation Studies Comparative Studies Evaluation Research Multicenter Studies Scales Aged: 65+ years Middle Aged: 45-64 years Aged, 80 & over Adult: 19-44 years Female Male ab: The uremic state affects myocardial structure, bringing about, among other things, interstitial calcium deposition. Abnormalities of myocardial structure can be assessed quantitatively and noninvasively during life by the analysis of the gray-level distribution of conventional two-dimensional echocardiograms. The aim of this study was to evaluate the role of quantitative echocardiography in providing information on myocardial structure in patients under maintenance hemodialysis and to relate the ultrasonic findings with abnormalities in calcium-phosphate metabolism. Forty patients undergoing dialysis without abnormalities in left ventricular regional and global function and 17 hypertensive patients with comparable left ventricular hypertrophy were studied. The distribution of the gray levels within a region of interest in the interventricular septum was analyzed off-line by an array processor-based computer. Compared with hypertensive patients, patients undergoing dialysis showed a greater myocardial echogenicity (mean 92 +/- 20 versus 72 +/- 15; p = 0.004) and a reduced homogeneity of distribution of gray levels (entropy 4.5 +/- 0.2 versus 4.2 +/- 0.2, p < 0.01; uniformity 0.010 +/- 0.003 versus 0.020 +/- 0.004, p < 0.005). In the same patients, a significant negative linear relation was found between entropy and calcium-phosphate product (r = -0.66; p = 0.001). Quantitative analysis of conventional two-dimensional echocardiograms allows the detection of a pathologic myocardial structure in patients under maintenance hemodialysis with normal left ventricular function. These abnormalities are related to disorders of calcium-phosphate metabolism and bear no relationship to the degree of left ventricular hypertrophy. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|