Is visceral obesity associated with colorectal cancer? The first volumetric study using all CT slices.
Purpose: We aimed to examine the possible relationship between abdominal adiposity parameters and the presence of colorectal cancer (CRC) and between these adiposity parameters and various histopathologic findings of the tumor.Methods: A total of 60 control subjects and 111 CRC patients, 63 with ear...
| Publicado en: | Diagnostic & Interventional Radiology Vol. 25; no. 5; pp. 338 - 346 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
Sep2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138625925&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138625925 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13053825 39NM jtl: Diagnostic & Interventional Radiology issn: 13053825 maglogo: N pubinfo: dt: Sep2019 vid: 25 iid: 5 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 138625925 138625925 NLM31287430 138625925 10.5152/dir.2019.18350 NLM31287430 138625925 ppf: 338 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Is visceral obesity associated with colorectal cancer? The first volumetric study using all CT slices. aug: au: Akay, Sinan Urkan, Murat Balyemez, Uğurcan Erşen, Mehmet Taşar, Mustafa affil: Department of Radiology University of Health Sciences, Gülhane Training and Research Hospital, Ankara, Turkey sug: subj: Obesity Obesity Complications Colorectal Neoplasms Complications Colorectal Neoplasms Tomography, X-Ray Computed Methods Middle Age Female Male Middle Aged: 45-64 years Female Male ab: Purpose: We aimed to examine the possible relationship between abdominal adiposity parameters and the presence of colorectal cancer (CRC) and between these adiposity parameters and various histopathologic findings of the tumor.Methods: A total of 60 control subjects and 111 CRC patients, 63 with early-stage and 48 with advanced-stage disease, were enrolled. Medical data and abdominopelvic computed tomography (CT) examinations of each study group were retrospectively reviewed. Abdominal adiposity parameters, including visceral adipose tissue (VAT) volume, subcutaneous adipose tissue (SAT) volume, and total adipose tissue (TAT) volume, were calculated on all slices of the CT examinations with specialized software, and results for each study group were compared. Adiposity parameters were also compared with tumor histopathologic findings.Results: We found lower VAT and higher SAT volumes in advanced-stage CRC patients, compared with the early-stage group. However, this relationship was not statistically significant (P = 0.721 for VAT and P = 0.432 for SAT volumes). We detected significantly lower VAT and SAT volumes in the early-stage CRC group compared with the control group (P = 0.014 for both). There was no significant relationship between TAT volumes and the study groups (P = 0.06). No statistically significant relationship was detected between adipose tissue parameters and histopathologic features of the CRC group (P > 0.05).Conclusion: We found statistically significant lower VAT and SAT volumes in patients with early-stage CRC compared with the control group. Volumetric adipose tissue measurements may be more accurate than area measurements and can easily be performed on abdominopelvic CT examination, which is the routine imaging modality for CRC patients. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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