Acoustic quantification indexes of left ventricular size and function: effects of signal averaging.
Background: The aim of this study was to evaluate the clinical utility of using signal-averaged acoustic quantification (SAAQ) waveforms for improved assessment of left ventricular (LV) size and function.Methods and Results: Four separate protocols were performed in 47 subjects. SAAQ waveforms were...
| Published in: | Journal of the American Society of Echocardiography Vol. 11; no. 8; pp. 792 - 803 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Published: |
Elsevier B.V.
1998 Aug
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138644989&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138644989 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08947317 4CO jtl: Journal of the American Society of Echocardiography issn: 08947317 maglogo: N pubinfo: dt: 1998 Aug vid: 11 iid: 8 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 138644989 NLM9719091 NLM9719091 138644989 ppf: 792 ppct: 11 formats: tig: atl: Acoustic quantification indexes of left ventricular size and function: effects of signal averaging. aug: au: Mor-Avi, V Vignon, P Bales, A C Spencer, K T Lang, R M affil: Department of Medicine, The University of Chicago Medical Center, Illinois 60637, USA sug: subj: Echocardiography Methods Signal Processing, Computer Assisted Ventricular Function, Left Physiology Hypertrophy, Left Ventricular Adrenergic beta-Antagonists Case Control Studies Echocardiography, Transesophageal Adult Ventricular Function, Left Drug Effects Dobutamine Propanolamines Image Processing, Computer Assisted Adrenergic beta-Agonists Middle Age Female Pilot Studies Male Clinical Assessment Tools Questionnaires Scales Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Background: The aim of this study was to evaluate the clinical utility of using signal-averaged acoustic quantification (SAAQ) waveforms for improved assessment of left ventricular (LV) size and function.Methods and Results: Four separate protocols were performed in 47 subjects. SAAQ waveforms were used to assess alterations in LV function induced by dobutamine (15 microg/kg per minute) and esmolol (200 microg/kg per minute) in eight normal subjects. Subsequently, we analyzed SAAQ waveforms obtained in 12 patients with LV dysfunction secondary to dilated cardiomyopathy and 12 age-matched normal subjects. Finally, we developed computer software for monitoring of LV function on the basis of continuous acquisition and repeated analysis of SAAQ waveforms. We compared the interbeat variability in indexes of LV function obtained from raw AQ and SAAQ during 10 minutes of steady-state monitoring in eight patients undergoing transesophageal echocardiography. The feasibility of long-term monitoring in the intensive care setting was then studied in seven patients undergoing abdominal surgery. Our analysis tracked variations in LV function induced by dobutamine and esmolol. Significant differences in all measured indexes were found between normal subjects and patients with dilated cadiomyopathy. Signal averaging during steady-state monitoring significantly reduced the interbeat variability of all indexes (21% to 42%). In the operating room, the SAAQ monitoring system tracked hemodynamic changes in close agreement with invasive measurements.Conclusions: SAAQ allows fast and easy quantification of LV function and can track hemodynamic trends in the operating room setting. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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