Direct quantification of transmitral flow volume with dynamic 3-dimensional digital color Doppler: a validation study in an animal model.
Accurately quantifying transmitral flow volume is clinically important not only as a measure of cardiac output, but also as a value from which to subtract aortic flow, for determining the severity of mitral regurgitation. However, controversy exists over the accuracy of pulsed Doppler for mitral flo...
| Publicado en: | Journal of the American Society of Echocardiography Vol. 15; no. 1; pp. 55 - 63 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
2002 Jan
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138699230&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138699230 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08947317 4CO jtl: Journal of the American Society of Echocardiography issn: 08947317 maglogo: N pubinfo: dt: 2002 Jan vid: 15 iid: 1 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 138699230 138699230 NLM11781555 138699230 10.1067/mje.2002.116716 NLM11781555 138699230 ppf: 55 ppct: 8 formats: tig: atl: Direct quantification of transmitral flow volume with dynamic 3-dimensional digital color Doppler: a validation study in an animal model. aug: au: Rusk, Rosemary A Li, Xiang-Ning Mori, Yoshiki Irvine, Timothy Jones, Michael Zetts, Arthur D Kenny, Antoinette Sahn, David J affil: Oregon Health Sciences University, Portland, USA sug: subj: Echocardiography, Doppler, Color Mitral Valve Physiology Echocardiography, Three-Dimensional Mitral Valve Blood Flow Velocity Physiology Sheep Ventricular Function Models, Biological Aortic Valve Physiology Heart Ventricle Stroke Volume Physiology Aortic Valve Observer Bias Animal Studies Validation Studies Comparative Studies Evaluation Research Multicenter Studies ab: Accurately quantifying transmitral flow volume is clinically important not only as a measure of cardiac output, but also as a value from which to subtract aortic flow, for determining the severity of mitral regurgitation. However, controversy exists over the accuracy of pulsed Doppler for mitral flow quantification because of the complexity of mitral flow geometry and dynamic changes in flow profile and flow area. To explore the feasibility of directly quantifying transmitral flow volume with a newly developed dynamic 3-dimensional digital color Doppler technique, this in vivo experimental study was conducted to validate the method. Eight open chest sheep were imaged with a multiplane transesophageal (TEE) probe placed on the heart for digital 3-dimensional gated acquisition of mitral inflow over a 180-degree acquisition. The digital velocity data were contour detected for flow area after computing the velocity vectors and flow profile perpendicular to a spherical 3-dimensional surface across the mitral annulus. Flow areas and actual velocities were then integrated in time and space and the resulting flow volumes were compared with those obtained by a reference electromagnetic flowmeter on the aorta for 26 steady hemodynamic states. The flow volumes correlated closely to the electromagnetic references (y = 0.87x + 2.49, r = 0.92, SEE = 1.9 Ml per beat). Our study shows that transmitral flow volume can be accurately determined in vivo by this dynamic 3-dimensional digital color Doppler flow quantification method. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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