Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells.

Drug resistance to temozolomide (TMZ) contributes to the majority of tumor recurrence and treatment failure in patients with glioblastoma multiforme (GBM). Autophagy has been reported to play a role in chemoresistance in various types of cancer, including GBM. The anticancer effect of statins is aro...

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Publicado en:BioMed Research International pp. 1 - 13
Autores principales: Zhu, Zhiyuan, Zhang, Pingde, Li, Ning, Kiang, Karrie Mei Yee, Cheng, Stephen Yin, Wong, Vincent Kam-Wai, Leung, Gilberto Ka-Kit
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 9/23/2019
Acceso en línea:Ver este registro en EBSCOhost