Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells.

Drug resistance to temozolomide (TMZ) contributes to the majority of tumor recurrence and treatment failure in patients with glioblastoma multiforme (GBM). Autophagy has been reported to play a role in chemoresistance in various types of cancer, including GBM. The anticancer effect of statins is aro...

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Bibliographic Details

Published in:	BioMed Research International pp. 1 - 13
Main Authors:	Zhu, Zhiyuan, Zhang, Pingde, Li, Ning, Kiang, Karrie Mei Yee, Cheng, Stephen Yin, Wong, Vincent Kam-Wai, Leung, Gilberto Ka-Kit
Format:	pictorial research tables/charts Journal Article
Published:	Wiley-Blackwell 9/23/2019
Online Access:	View this record in EBSCOhost