Semantic Provenance Graph for Reproducibility of Biomedical Research Studies: Generating and Analyzing Graph Structures from Published Literature...The 17th World Congress of Medical and Health Informatics, 25-30 August 2019, Lyon, France

Objective: To characterize the scientific reproducibility of biomedical research studies by query and analysis of semantic provenance graphs generated from provenance metadata terms extracted from PubMed articles. Methods. We develop a new semantic provenance graph generation algorithm that uses a p...

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Publicado en:Studies in Health Technology & Informatics Vol. 264; pp. 328 - 333
Autores principales: Sahoo, Satya S., Valdez, Joshua, Rueschman, Michael, Kim, Matthew
Formato: proceedings research tables/charts Journal Article
Publicado: Sage Publications Inc. 2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2019
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Semantic Provenance Graph for Reproducibility of Biomedical Research Studies: Generating and Analyzing Graph Structures from Published Literature...The 17th World Congress of Medical and Health Informatics, 25-30 August 2019, Lyon, France
      aug:
        au:
          Sahoo, Satya S.
          Valdez, Joshua
          Rueschman, Michael
          Kim, Matthew
        affil: Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA
      sug:
        subj:
          Reproducibility of Results
          Semantic Analysis
          Metadata
          Research, Medical
          PubMed
          Algorithms
          Database Design
          Ontologies
          Health Information Systems
          Data Analysis, Statistical
          Congresses and Conferences France
          France
          Human
          Funding Source
      ab: Objective: To characterize the scientific reproducibility of biomedical research studies by query and analysis of semantic provenance graphs generated from provenance metadata terms extracted from PubMed articles. Methods. We develop a new semantic provenance graph generation algorithm that uses a provenance ontology developed as part of the Provenance for Clinical and Health Research (ProvCaRe) project. The ProvCaRe project has processed and extracted provenance metadata from more than 1.6 million full text articles from the PubMed database. Results. The semantic provenance graph generation algorithm is evaluated using provenance terms extracted from 75 selected articles describing sleep medicine research studies. In addition, we use eight provenance queries to evaluate the quality of semantic provenance graphs generated by the new algorithm. Conclusion. The ProvCaRe project has created a unique resource to characterize the reproducibility of biomedical research studies and the semantic provenance graph generation algorithm enables users to effectively query and analyze the provenance metadata in the ProvCaRe knowledge repository.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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