Association between early prenatal exposure to ambient air pollution and birth defects: evidence from newborns in Xi'an, China.
Background The aim of this study was to investigate an association between birth defects and exposure to sulfur dioxide (SO2), nitrogen dioxide (NO2) and particles ≤10 μm in an aerodynamic diameter (PM10) during early pregnancy in Xi'an, China. Methods Birth defect data were from the Birth Defects M...
| Publicado en: | Journal of Public Health Vol. 41; no. 3; pp. 494 - 502 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Oxford University Press / USA
Sep2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139059056&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139059056 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17413842 1CA0 jtl: Journal of Public Health issn: 17413842 maglogo: N pubinfo: dt: Sep2019 vid: 41 iid: 3 pid: 622 pub: Oxford University Press / USA artinfo: ui: 139059056 139059056 139059056 10.1093/pubmed/fdy137 139059056 ppf: 494 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Association between early prenatal exposure to ambient air pollution and birth defects: evidence from newborns in Xi'an, China. aug: au: Wang, Lingling Xiang, Xiaomei Mi, Baibing Song, Hui Dong, Min Zhang, Shuiping Bi, Yuxue Zhao, Yaling Li, Qiang Zhang, Qi Zhang, Li Yan, Hong Wang, Duolao Dang, Shaonong affil: Xi'an Jiaotong University, Health Science Center, No. 76, Yanta West Road, Xi'an, Shaanxi Province, PR China sug: subj: Air Pollution China Air Pollution Adverse Effects Abnormalities Risk Factors Prenatal Care Human China Incidence Prenatal Exposure Delayed Effects Pregnancy Female Funding Source Sulfur Compounds Nitrogen Compounds Environmental Exposure Female ab: Background The aim of this study was to investigate an association between birth defects and exposure to sulfur dioxide (SO2), nitrogen dioxide (NO2) and particles ≤10 μm in an aerodynamic diameter (PM10) during early pregnancy in Xi'an, China. Methods Birth defect data were from the Birth Defects Monitoring System of Xi'an, and data on ambient air pollutants during 2010–15 were from the Xi'an Environmental Protection Bureau. A generalized additive model (GAM) was used to investigate the relationship between birth defects and ambient air pollutants. Results Among the 8865 cases with birth defects analyzed, the overall incidence of birth defects was 117.33 per 10 000 infants. Ambient air pollutant exposure during the first trimester increased the risk of birth defects by 10.3% per 10 μg/m3 increment of NO2 and 3.4% per 10 μg/m3 increment of PM10. No significant association was found between birth defects and SO2. Moreover, NO2 increased risk of neural tube defects, congenital heart disease, congenital polydactyly, cleft palate, digestive system abnormalities and gastroschisis, and PM10 was associated with congenital heart disease and cleft lip with or without cleft palate. Conclusions Chinese women should avoid exposure to high levels of NO2 and PM10 during the first 3 months of pregnancy. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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